⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL2748684 | 0.97 | — | — | |
| SCHEMBL11513414 | 0.97 | — | — | |
| Diethylamine SCHEMBL20946172 | 0.91 | TP53 (0.47) | — | |
| Formic Acid SCHEMBL17362051 | 0.86 | CA2 (0.36) | — | |
| SCHEMBL242031 | 0.77 | — | — | |
| SCHEMBL15673083 | 0.76 | CA1 (0.36) | — | |
| SCHEMBL7163145 | 0.76 | — | — | |
| SCHEMBL3871336 | 0.74 | — | — | |
| SCHEMBL27252944 | 0.74 | CA2 (0.41) | — | |
| SCHEMBL3043384 | 0.74 | POLB (0.44) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1832 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4182322-B1 | PYRIDO OXAZINE DERIVATIVES AS ALK5 INHIBITORS | CHIESI FARM SPA (IT) | 2024-04-24 | — | — | EP | claimed |
| US-20240116947-A1 | PYRIDO OXAZINE DERIVATIVES AS ALK5 INHIBITORS | CHIESI FARMACEUTICI S.P.A. (IT) | 2024-04-11 | — | — | US | claimed |
| EP-4182322-A1 | PYRIDO OXAZINE DERIVATIVES AS ALK5 INHIBITORS | Chiesi Farmaceutici S.p.A. (IT) | 2023-05-24 | — | — | EP | claimed |
| EP-2694505-B1 | HSP90 INHIBITORS | SLOAN KETTERING INST CANCER RES (US) | 2022-04-27 | — | — | EP | claimed |
| US-10201623-B2 | HSP90-targeted cardiac imaging and therapy | MEMORIAL SLOAN KETTERING CANCER CENTER (US) | 2019-02-12 | — | — | US | claimed |
| US-9745305-B2 | Modulators of methyl modifying enzymes, compositions and uses thereof | CONSTELLATION PHARMACEUTICALS, INC. (US) | 2017-08-29 | — | — | US | claimed |
| EP-2970305-B1 | MODULATORS OF METHYL MODIFYING ENZYMES, COMPOSITIONS AND USES THEREOF | CONSTELLATION PHARMACEUTICALS INC (US) | 2017-02-22 | — | — | EP | claimed |
| EP-3091984-A1 | SUBSTITUTED BENZOXAZINE AND RELATED COMPOUNDS | The J. David Gladstone Institutes, A Testamentary Trust Established under The Will of J. David Gladstone (US) | 2016-11-16 | — | — | EP | claimed |
| US-20160264577-A1 | HSP90 INHIBITORS | SLOAN-KETTERING INSTITUTE FOR CANCER RESEARCH | 2016-09-15 | — | — | US | claimed |
| EP-2970305-A1 | MODULATORS OF METHYL MODIFYING ENZYMES, COMPOSITIONS AND USES THEREOF | Constellation Pharmaceuticals, Inc. (US) | 2016-01-20 | — | — | EP | claimed |
| EP-0495594-B1 | Sulphonamide derivatives | ZENECA LTD (GB) | 1996-03-20 | — | — | EP | claimed |
| US-5414084-A | Reaction 2-aminopyrimidine or amino-1,3,5-triazine derivative; purity; by-product inhibition | HOECHST AKTIENGESELLSCHAFT (DE) | 1995-05-09 | — | — | US | claimed |
| EP-0589018-A1 | AMINES AS INHIBITORS OF SQUALENE SYNTHASE | ZENECA LIMITED (GB) | 1994-03-30 | — | — | EP | claimed |
| WO-1993020807-A1 | AMINES AS INHIBITORS OF SQUALENE SYNTHASE | ZENECA LIMITED (GB) | 1993-10-28 | — | — | WO | claimed |
| US-5180826-A | Multistage reaction of chlorosulfonylisocyanate and methane sulfonylethylamine and reacting with aminopyrimidine | LONZA LTD. (CH) | 1993-01-19 | — | — | US | claimed |
| EP-0495594-A1 | Sulphonamide derivatives | ZENECA LIMITED (GB) | 1992-07-22 | — | — | EP | claimed |
| US-5011928-A | Analgesic and antiinflammatory derivatives of 1-acyl-4-arylalkylpiperazines | FABRICA ESPANOLA DE PRODUCTOS QUIMICOS Y FARMECEUTI COS S.A. (FAES) (ES) | 1991-04-30 | — | — | US | claimed |
| EP-0385044-A1 | New piperidine derivatives as antihistaminics | FABRICA ESPANOLA DE PRODUCTOS QUIMICOS Y FARMACEUTICOS, S.A. (FAES) (ES) | 1990-09-05 | — | — | EP | claimed |
| EP-0074894-B1 | PROCESS FOR THE PURIFICATION OF A GASEOUS MIXTURE CONTAINING UNDESIRABLE GASEOUS COMPOUNDS | COMPAGNIE FRANCAISE DE RAFFINAGE Société anonyme dite: (FR) | 1985-01-02 | — | — | EP | claimed |
| US-4170547-A | SOLVENT EXTRACTION | COMPAGNIE FRANCAISE DE RAFFINAGE (FR) | 1979-10-09 | — | — | US | claimed |