Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | MDM2 | Q00987 | 2/20 | 0.41 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.41 |
| ▸ | CMA1 | P23946 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | LPO | P22079 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25197107 | 1.00 | HRH3 (0.43) | HRH3LMNAHTTMDM2SIGMAR1 | |
| SCHEMBL31427148 | 1.00 | HRH3 (0.43) | HRH3LMNAHTTMDM2SIGMAR1 | |
| SCHEMBL25215671 | 1.00 | HRH3 (0.43) | HRH3LMNAHTTMDM2SIGMAR1 | |
| SCHEMBL25215892 | 0.83 | ROCK2 (0.47) | HRH3SIGMAR1KDM4EALDH1A1 | |
| SCHEMBL31427147 | 0.83 | ROCK2 (0.47) | HRH3SIGMAR1KDM4EALDH1A1 | |
| SCHEMBL31427146 | 0.83 | ROCK2 (0.47) | HRH3SIGMAR1KDM4EALDH1A1 | |
| SCHEMBL25211576 | 0.83 | ROCK2 (0.47) | HRH3SIGMAR1KDM4EALDH1A1 | |
| SCHEMBL31427144 | 0.80 | ROCK2 (0.51) | HRH3SIGMAR1KDM4EALDH1A1 | |
| SCHEMBL25198645 | 0.74 | RIPK1 (0.39) | — | |
| SCHEMBL25198448 | 0.74 | BRD4 (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116178337-B | Benzodiazepine compounds and their use as Rho kinase inhibitors | 成都奥睿药业有限公司 | 2025-04-25 | — | — | CN | disclosed |