Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.39 |
| ▸ | HTT | P42858 | 3/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | IDO1 | P14902 | 1/20 | 0.38 |
| ▸ | TDO2 | P48775 | 1/20 | 0.38 |
| ▸ | IDO2 | Q6ZQW0 | 1/20 | 0.38 |
| ▸ | ALDH3A1 | P30838 | 4/20 | 0.37 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.35 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.35 |
| ▸ | ACHE | P22303 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | DRD2 | P14416 | 1/20 | 0.33 |
| ▸ | DRD4 | P21917 | 1/20 | 0.33 |
| ▸ | LTA4H | P09960 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31428480 | 0.89 | ALDH1A1 (0.43) | ALDH1A1HTTSMN1; SMN2MAPTMAPK1 | |
| SCHEMBL31429031 | 0.86 | MAPT (0.41) | ALDH1A1HTTSMN1; SMN2MAPTMAPK1 | |
| SCHEMBL30163516 | 0.86 | ALDH1A1 (0.37) | ALDH1A1HTTSMN1; SMN2MAPTMAPK1 | |
| SCHEMBL31428674 | 0.85 | ALDH1A1 (0.40) | ALDH1A1HTTSMN1; SMN2MAPTMAPK1 | |
| SCHEMBL31428584 | 0.85 | ALDH1A1 (0.42) | ALDH1A1HTTSMN1; SMN2MAPTMAPK1 | |
| SCHEMBL24975442 | 0.81 | ALDH1A1 (0.35) | ALDH1A1HTTSMN1; SMN2MAPTMAPK1 | |
| SCHEMBL31428751 | 0.81 | ALDH1A1 (0.35) | ALDH1A1HTTSMN1; SMN2MAPTMAPK1 | |
| SCHEMBL31428451 | 0.80 | MAPT (0.49) | ALDH1A1HTTSMN1; SMN2MAPTMAPK1 | |
| SCHEMBL31428622 | 0.78 | PDCD1 (0.44) | ALDH1A1HTTSMN1; SMN2MAPTMAPK1 | |
| SCHEMBL31428590 | 0.78 | FKBP1A (0.41) | ALDH1A1HTTSMN1; SMN2MAPTMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250091994-A1 | RAS/RAF BINDING INHIBITOR COMPOUND | NATIONAL UNIVERSITY CORPORATION KOBE UNIVERSITY (JP) | 2025-03-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250091994-A1 | RAS/RAF BINDING INHIBITOR COMPOUND | BRAF, RAF1, NRAS | ALDH1A1 2352/4885HTT 4442/4885SMN1; SMN2 4832/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.