Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.54 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 5/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.51 |
| ▸ | MEN1 | O00255 | 3/20 | 0.51 |
| ▸ | PKM | P14618 | 1/20 | 0.51 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.49 |
| ▸ | PRKDC | P78527 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.48 |
| ▸ | USP2 | O75604 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31428485 | 0.82 | LRRK2 (0.52) | MAPTSMN1; SMN2MAPK1KMT2AALDH1A1 | |
| SCHEMBL30163514 | 0.78 | ALDH1A1 (0.60) | MAPTSMN1; SMN2MAPK1KMT2AMEN1 | |
| SCHEMBL30163481 | 0.78 | KMT2A (0.68) | MAPTSMN1; SMN2ALOX15MAPK1KMT2A | |
| SCHEMBL31428848 | 0.75 | MAPT (0.60) | MAPTSMN1; SMN2MAPK1KMT2AMEN1 | |
| SCHEMBL31428936 | 0.74 | ALDH1A1 (0.59) | MAPTSMN1; SMN2MAPK1KMT2AMEN1 | |
| SCHEMBL30163499 | 0.73 | MAPT (0.56) | MAPTSMN1; SMN2MAPK1KMT2AMEN1 | |
| SCHEMBL1643927 | 0.73 | ALDH1A1 (0.76) | MAPTSMN1; SMN2ALOX15MAPK1KMT2A | |
| SCHEMBL31429081 | 0.72 | MAPT (0.53) | MAPTSMN1; SMN2MAPK1KMT2AMEN1 | |
| SCHEMBL30163547 | 0.72 | ALDH1A1 (0.53) | MAPTSMN1; SMN2MAPK1KMT2AMEN1 | |
| SCHEMBL31428731 | 0.72 | MAPT (0.55) | MAPTSMN1; SMN2MAPK1KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250091994-A1 | RAS/RAF BINDING INHIBITOR COMPOUND | NATIONAL UNIVERSITY CORPORATION KOBE UNIVERSITY (JP) | 2025-03-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250091994-A1 | RAS/RAF BINDING INHIBITOR COMPOUND | BRAF, RAF1, NRAS | MAPT 4513/4885SMN1; SMN2 4832/4885ALOX15 4555/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.