Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 6/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | CES1 | P23141 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.38 |
| ▸ | ACACA | Q13085 | 1/20 | 0.37 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31428762 | 0.89 | MAPT (0.47) | MAPTMAPK1TDP1ALDH1A1SMN1; SMN2 | |
| SCHEMBL31428577 | 0.85 | ALDH1A1 (0.50) | MAPTMAPK1TDP1ALDH1A1SMN1; SMN2 | |
| SCHEMBL31428705 | 0.83 | ALDH1A1 (0.61) | MAPTMAPK1TDP1ALDH1A1SMN1; SMN2 | |
| SCHEMBL31429004 | 0.82 | MAPT (0.53) | MAPTMAPK1TDP1ALDH1A1SMN1; SMN2 | |
| SCHEMBL30163485 | 0.82 | MAPT (0.53) | MAPTMAPK1TDP1ALDH1A1SMN1; SMN2 | |
| SCHEMBL31428668 | 0.77 | ALDH1A1 (0.53) | MAPTMAPK1TDP1ALDH1A1SMN1; SMN2 | |
| SCHEMBL31428526 | 0.76 | ALDH1A1 (0.53) | MAPTMAPK1TDP1ALDH1A1SMN1; SMN2 | |
| SCHEMBL31428589 | 0.76 | MAPT (0.53) | MAPTMAPK1TDP1ALDH1A1SMN1; SMN2 | |
| SCHEMBL31428729 | 0.75 | ALDH1A1 (0.54) | MAPTMAPK1TDP1ALDH1A1SMN1; SMN2 | |
| SCHEMBL30163499 | 0.75 | MAPT (0.56) | MAPTMAPK1TDP1ALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250091994-A1 | RAS/RAF BINDING INHIBITOR COMPOUND | NATIONAL UNIVERSITY CORPORATION KOBE UNIVERSITY (JP) | 2025-03-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250091994-A1 | RAS/RAF BINDING INHIBITOR COMPOUND | BRAF, RAF1, NRAS | MAPT 4513/4885MAPK1 140/4885TDP1 3630/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.