Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | ESR1 | P03372 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.41 |
| ▸ | CES1 | P23141 | 1/20 | 0.41 |
| ▸ | ACVR1 | Q04771 | 7/20 | 0.36 |
| ▸ | IDO1 | P14902 | 2/20 | 0.36 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.35 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.35 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31428974 | 0.94 | MAPT (0.41) | MAPTSMN1; SMN2HTTALDH1A1MAPK1 | |
| SCHEMBL31428880 | 0.87 | ALDH1A1 (0.43) | MAPTSMN1; SMN2HTTALDH1A1MAPK1 | |
| SCHEMBL30163673 | 0.86 | PDCD1 (0.40) | MAPTSMN1; SMN2HTTALDH1A1MAPK1 | |
| SCHEMBL31428415 | 0.84 | PDCD1 (0.41) | MAPTSMN1; SMN2HTTALDH1A1MAPK1 | |
| SCHEMBL31429054 | 0.83 | LRRK2 (0.34) | MAPTSMN1; SMN2HTTALDH1A1MAPK1 | |
| SCHEMBL31428878 | 0.82 | MAPT (0.44) | MAPTSMN1; SMN2HTTALDH1A1MAPK1 | |
| SCHEMBL30163577 | 0.81 | GRM2 (0.52) | MAPTSMN1; SMN2HTTALDH1A1MAPK1 | |
| SCHEMBL31428638 | 0.78 | ALDH1A1 (0.44) | MAPTSMN1; SMN2HTTALDH1A1MAPK1 | |
| SCHEMBL31428874 | 0.78 | ALDH1A1 (0.41) | MAPTSMN1; SMN2HTTALDH1A1MAPK1 | |
| SCHEMBL31428670 | 0.77 | MAPT (0.54) | MAPTSMN1; SMN2HTTALDH1A1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250091994-A1 | RAS/RAF BINDING INHIBITOR COMPOUND | NATIONAL UNIVERSITY CORPORATION KOBE UNIVERSITY (JP) | 2025-03-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250091994-A1 | RAS/RAF BINDING INHIBITOR COMPOUND | BRAF, RAF1, NRAS | MAPT 4513/4885SMN1; SMN2 4832/4885HTT 4442/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.