Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RECQL | P46063 | 2/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.53 |
| ▸ | KMO | O15229 | 1/20 | 0.47 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.42 |
| ▸ | DAO | P14920 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 3/20 | 0.40 |
| ▸ | RAB9A | P51151 | 3/20 | 0.40 |
| ▸ | POLB | P06746 | 3/20 | 0.40 |
| ▸ | TSHR | P16473 | 3/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | PTAFR | P25105 | 1/20 | 0.39 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.36 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4287336 | 0.79 | RECQL (0.56) | RECQLCYP1A2KMOADRA2ADAO | |
| SCHEMBL30755148 | 0.79 | RECQL (0.56) | RECQLCYP1A2KMOADRA2ADAO | |
| SCHEMBL4319982 | 0.79 | CYP1A2 (0.70) | RECQLCYP1A2KMOADRA2ADAO | |
| SCHEMBL31236306 | 0.79 | CYP1A2 (0.70) | RECQLCYP1A2KMOADRA2ADAO | |
| SCHEMBL13217 | 0.76 | RECQL (0.61) | RECQLCYP1A2KMOADRA2ADAO | |
| SCHEMBL7331551 | 0.74 | RECQL (0.69) | RECQLCYP1A2KMOADRA2ADAO | |
| SCHEMBL29487638 | 0.73 | CYP1A2 (0.62) | RECQLCYP1A2KMOADRA2ADAO | |
| SCHEMBL5565705 | 0.73 | CYP1A2 (0.62) | RECQLCYP1A2KMOADRA2ADAO | |
| SCHEMBL30839555 | 0.72 | CYP1A2 (0.57) | RECQLCYP1A2KMOADRA2ADAO | |
| SCHEMBL3076519 | 0.72 | RECQL (0.61) | RECQLCYP1A2KMOADRA2ADAO |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250092014-A1 | COMPOUNDS AND METHODS OF ACTIVATING LIPOPROTEIN LIPASE | METREA BIOSCIENCES INC (US) | 2025-03-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250092014-A1 | COMPOUNDS AND METHODS OF ACTIVATING LIPOPROTEIN LIPASE | LPL, LIPA, PNLIP | RECQL 1592/4885CYP1A2 973/4885KMO 2002/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.