SCHEMBL31429573

SCHEMBL31429573

COc1ccc(C(NC(=O)OCc2cccc3c2Cc2ccccc2-3)c2ccc(OCC(=O)O)cc2)c(OC)c1

nearest known ligand 0.41

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
▸ KMT2A Q03164 6/20 0.41
▸ MEN1 O00255 5/20 0.41
▸ THRA P10827 1/20 0.40
▸ THRB P10828 1/20 0.40
▸ ADAMTS5 Q9UNA0 3/20 0.38
▸ LMNA P02545 3/20 0.37
▸ HTT P42858 3/20 0.37
▸ SMN1; SMN2 Q16637 3/20 0.37
▸ ALDH1A1 P00352 2/20 0.37
▸ MAPT P10636 2/20 0.37
▸ HPGD P15428 2/20 0.37
▸ NPC1 O15118 2/20 0.36
▸ RAB9A P51151 2/20 0.36
▸ PTGDR2 Q9Y5Y4 1/20 0.35
▸ KDM4E B2RXH2 1/20 0.35
▸ MITF O75030 1/20 0.35
▸ TP53 P04637 1/20 0.35
▸ L3MBTL1 Q9Y468 1/20 0.35
▸ CD274 Q9NZQ7 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7860715 0.92 KMT2A (0.42) KMT2AMEN1LMNAHTTSMN1; SMN2
SCHEMBL8769214 0.82 SRD5A1 (0.44) KMT2AMEN1LMNAALDH1A1MAPT
SCHEMBL29470540 0.80 KMT2A (0.45) KMT2AMEN1THRATHRBLMNA
SCHEMBL1745934 0.80 KMT2A (0.45) KMT2AMEN1THRATHRBLMNA
SCHEMBL1000962 0.80 KMT2A (0.45) KMT2AMEN1THRATHRBLMNA
SCHEMBL3367289 0.80 KMT2A (0.45) KMT2AMEN1THRATHRBLMNA
SCHEMBL31146900 0.80 KMT2A (0.45) KMT2AMEN1THRATHRBLMNA
SCHEMBL29368397 0.80 KMT2A (0.45) KMT2AMEN1THRATHRBLMNA
SCHEMBL14416300 0.73 KMT2A (0.42) KMT2AMEN1LMNAHTTSMN1; SMN2
SCHEMBL13523948 0.73 KMT2A (0.46) KMT2AMEN1HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119899305-A Polypeptide solid-phase synthesis carrier and preparation method thereof 西安蓝晓科技新材料股份有限公司 2025-04-29 — — CN disclosed
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