Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 6/20 | 0.42 |
| ▸ | MEN1 | O00255 | 5/20 | 0.42 |
| ▸ | HTT | P42858 | 4/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | LMNA | P02545 | 3/20 | 0.36 |
| ▸ | HPGD | P15428 | 3/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.36 |
| ▸ | RAB9A | P51151 | 4/20 | 0.36 |
| ▸ | NPC1 | O15118 | 3/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | MITF | O75030 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 2/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 2/20 | 0.35 |
| ▸ | CA2 | P00918 | 2/20 | 0.35 |
| ▸ | ACHE | P22303 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31429573 | 0.92 | KMT2A (0.41) | KMT2AMEN1HTTALDH1A1LMNA | |
| SCHEMBL17192730 | 0.80 | KMT2A (0.45) | KMT2AMEN1HTTLMNASMN1; SMN2 | |
| SCHEMBL8410923 | 0.80 | KMT2A (0.45) | KMT2AMEN1HTTLMNASMN1; SMN2 | |
| SCHEMBL8769214 | 0.79 | SRD5A1 (0.44) | KMT2AMEN1ALDH1A1LMNAMAPT | |
| SCHEMBL30079703 | 0.79 | PNMT (0.40) | KMT2AMEN1RAB9ANPC1ATM | |
| SCHEMBL30079659 | 0.76 | PNMT (0.41) | RAB9ANPC1 | |
| SCHEMBL12555211 | 0.75 | KMT2A (0.47) | KMT2AMEN1ALDH1A1KDM4ETP53 | |
| SCHEMBL7984404 | 0.74 | PNMT (0.38) | KMT2AMEN1ALDH1A1LMNARAB9A | |
| SCHEMBL23118169 | 0.74 | ITGB3 (0.48) | KMT2AATM | |
| SCHEMBL10418084 | 0.73 | CD274 (0.41) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6228841-B1 | N-METHYLTYROSINE-ARGININE-PHENYLALANINE-N-METHYL-B-ALANINE OR ITS SALT; ANALGESIC FOR CANCER PAIN | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2001-05-08 | — | — | US | disclosed |
| EP-0861849-A1 | PEPTIDE DERIVATIVES | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 1998-09-02 | — | — | EP | disclosed |
| EP-0850950-A1 | PEPTIDE DERIVATIVES | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 1998-07-01 | — | — | EP | disclosed |