Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PGR | P06401 | 13/20 | 0.46 |
| ▸ | PDE4A | P27815 | 5/20 | 0.43 |
| ▸ | PDE4B | Q07343 | 5/20 | 0.43 |
| ▸ | PDE4C | Q08493 | 5/20 | 0.43 |
| ▸ | PDE4D | Q08499 | 5/20 | 0.43 |
| ▸ | PDE3B | Q13370 | 5/20 | 0.43 |
| ▸ | PDE3A | Q14432 | 5/20 | 0.43 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.41 |
| ▸ | BACE1 | P56817 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31430278 | 0.94 | PGR (0.44) | PGRPDE4APDE4BPDE4CPDE4D | |
| SCHEMBL4291778 | 0.94 | PGR (0.44) | PGRPDE4APDE4BPDE4CPDE4D | |
| SCHEMBL25925116 | 0.90 | BACE1 (0.42) | PGRPDE4APDE4BPDE4CPDE4D | |
| SCHEMBL31430249 | 0.87 | BACE1 (0.40) | PGRPDE4APDE4BPDE4CPDE4D | |
| SCHEMBL1222942 | 0.86 | MAPK14 (0.42) | PGRPDE4APDE4BPDE4CPDE4D | |
| SCHEMBL16437334 | 0.85 | MAPK14 (0.42) | PGRPDE4APDE4BPDE4CPDE4D | |
| SCHEMBL16427562 | 0.83 | BACE1 (0.38) | PGRBACE1 | |
| SCHEMBL31116974 | 0.81 | PGR (0.47) | PGRPDE4APDE4BPDE4CPDE4D | |
| SCHEMBL1224061 | 0.79 | MAPK14 (0.46) | EPHX2BACE1 | |
| SCHEMBL16442023 | 0.79 | BACE1 (0.42) | BACE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025092818-A1 | PYRIDINE DERIVATIVE AND USE THEREOF IN MEDICINE | 康百达（四川）生物医药科技有限公司 | 2025-05-08 | — | — | WO | disclosed |
| CN-119462695-A | Pyridine derivative and application thereof | 康百达（四川）生物医药科技有限公司 | 2025-02-18 | — | — | CN | disclosed |