Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PGR | P06401 | 9/20 | 0.44 |
| ▸ | PDE4A | P27815 | 5/20 | 0.43 |
| ▸ | PDE4B | Q07343 | 5/20 | 0.43 |
| ▸ | PDE4C | Q08493 | 5/20 | 0.43 |
| ▸ | PDE4D | Q08499 | 5/20 | 0.43 |
| ▸ | PDE3B | Q13370 | 5/20 | 0.43 |
| ▸ | PDE3A | Q14432 | 5/20 | 0.43 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.40 |
| ▸ | BACE1 | P56817 | 3/20 | 0.40 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.38 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.38 |
| ▸ | LPL | P06858 | 1/20 | 0.37 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4291778 | 1.00 | PGR (0.44) | PGRPDE4APDE4BPDE4CPDE4D | |
| SCHEMBL31430232 | 0.94 | PGR (0.46) | PGRPDE4APDE4BPDE4CPDE4D | |
| SCHEMBL25925116 | 0.92 | BACE1 (0.42) | PGRPDE4APDE4BPDE4CPDE4D | |
| SCHEMBL31430249 | 0.90 | BACE1 (0.40) | PGRPDE4APDE4BPDE4CPDE4D | |
| SCHEMBL16427562 | 0.89 | BACE1 (0.38) | PGRBACE1PRMT5WDR77LPL | |
| SCHEMBL31116974 | 0.84 | PGR (0.47) | PGRPDE4APDE4BPDE4CPDE4D | |
| SCHEMBL1222942 | 0.83 | MAPK14 (0.42) | PGRPDE4APDE4BPDE4CPDE4D | |
| SCHEMBL1224221 | 0.83 | MAPK14 (0.45) | BACE1LPLLIPG | |
| SCHEMBL1222966 | 0.83 | MAPK14 (0.43) | BACE1PRMT5WDR77LPLLIPG | |
| SCHEMBL16437334 | 0.82 | MAPK14 (0.42) | PGRPDE4APDE4BPDE4CPDE4D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025092818-A1 | PYRIDINE DERIVATIVE AND USE THEREOF IN MEDICINE | 康百达（四川）生物医药科技有限公司 | 2025-05-08 | — | — | WO | disclosed |
| CN-119462695-A | Pyridine derivative and application thereof | 康百达（四川）生物医药科技有限公司 | 2025-02-18 | — | — | CN | disclosed |