SCHEMBL31432508

SCHEMBL31432508

COc1cc(O)c(O)cc1Br

nearest known ligand 0.65

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALOX5 P09917 1/20 0.50
PTGS2 P35354 1/20 0.50
ALDH1A1 P00352 1/20 0.45
GRIN2D O15399 1/20 0.45
GRIN3B O60391 1/20 0.45
GRIN1 Q05586 1/20 0.45
GRIN2A Q12879 1/20 0.45
GRIN2B Q13224 1/20 0.45
GRIN2C Q14957 1/20 0.45
GRIN3A Q8TCU5 1/20 0.45
HTR2A P28223 2/20 0.44
HTR2C P28335 2/20 0.44
EP300 Q09472 1/20 0.44
HTR2B P41595 1/20 0.44
TAAR1 Q96RJ0 1/20 0.44
HTT P42858 1/20 0.43
MAOB P27338 1/20 0.43
POLB P06746 1/20 0.43
L3MBTL1 Q9Y468 1/20 0.43
ALOX15 P16050 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8703848 0.88 ALOX5 (0.48) ALOX5PTGS2ALDH1A1GRIN2DGRIN3B
SCHEMBL15628229 0.88 ALOX5 (0.48) ALOX5PTGS2ALDH1A1GRIN2DGRIN3B
SCHEMBL7788363 0.88 ALOX5 (0.48) ALOX5PTGS2ALDH1A1GRIN2DGRIN3B
SCHEMBL19361333 0.88 ALOX5 (0.48) ALOX5PTGS2HTR2AHTR2CTAAR1
SCHEMBL31144218 0.84 ALOX5 (0.45) ALOX5PTGS2ALDH1A1GRIN2DGRIN3B
SCHEMBL25648797 0.84 ALOX5 (0.45) ALOX5PTGS2ALDH1A1GRIN2DGRIN3B
SCHEMBL8579736 0.83 ALOX5 (0.48) ALOX5PTGS2EP300HTTMAOB
SCHEMBL25346669 0.82 POLB (0.57) ALOX5PTGS2ALDH1A1HTR2AHTR2C
SCHEMBL21614378 0.82 DPP4 (0.46) ALOX5PTGS2ALDH1A1GRIN2DGRIN3B
SCHEMBL19737047 0.82 ALOX5 (0.44) ALOX5PTGS2ALDH1A1GRIN2DGRIN3B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4741389-A1 KAT6 INHIBITOR Shanghai Qilu Pharmaceutical Research and Development Centre Ltd. (CN) 2026-05-13 EP disclosed
WO-2025007873-A1 KAT6 INHIBITOR 上海齐鲁制药研究中心有限公司 2025-01-09 WO disclosed