Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 6/20 | 0.46 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.44 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.44 |
| ▸ | LCK | P06239 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.40 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.40 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.40 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.40 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.40 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.40 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.40 |
| ▸ | EP300 | Q09472 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31144189 | 1.00 | DPP4 (0.46) | DPP4ALOX5PTGS2LCKHPGD | |
| SCHEMBL17744476 | 0.83 | GAA (0.45) | DPP4ALOX5PTGS2LCKALDH1A1 | |
| SCHEMBL21404002 | 0.82 | GRIN2D (0.45) | LCKALDH1A1GRIN2DGRIN3BGRIN1 | |
| SCHEMBL31432508 | 0.82 | ALOX5 (0.50) | ALOX5PTGS2LCKALDH1A1GRIN2D | |
| SCHEMBL29663687 | 0.82 | GRIN2D (0.45) | LCKALDH1A1GRIN2DGRIN3BGRIN1 | |
| SCHEMBL11003488 | 0.82 | HTT (0.48) | DPP4HPGDTSHRHSD17B10 | |
| SCHEMBL7792597 | 0.80 | NPC1 (0.56) | DPP4HPGDTSHRHSD17B10 | |
| SCHEMBL69147 | 0.80 | HSD17B10 (0.52) | DPP4HPGDTSHRHSD17B10ALDH1A1 | |
| SCHEMBL28788044 | 0.80 | HTR2A (0.47) | GRIN2DGRIN3BGRIN1GRIN2AGRIN2B | |
| SCHEMBL19361333 | 0.80 | ALOX5 (0.48) | ALOX5PTGS2LCK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020007882-A1 | M-GUAIACOL DERIVATIVES, PREPARATION THEREOF, AND USES THEREOF | UNIVERSITE DE CAEN NORMANDIE (FR) | 2020-01-09 | — | — | WO | disclosed |