Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.53 |
| ▸ | TSHR | P16473 | 3/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.53 |
| ▸ | HSD17B3 | P37058 | 2/20 | 0.48 |
| ▸ | SLC6A3 | Q01959 | 4/20 | 0.46 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.46 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.41 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.40 |
| ▸ | CSF1R | P07333 | 1/20 | 0.40 |
| ▸ | KDR | P35968 | 1/20 | 0.40 |
| ▸ | FLT3 | P36888 | 1/20 | 0.40 |
| ▸ | GSK3A | P49840 | 1/20 | 0.40 |
| ▸ | GSK3B | P49841 | 1/20 | 0.40 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.40 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.40 |
| ▸ | SLK | Q9H2G2 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31432781 | 1.00 | ALDH1A1 (0.53) | ALDH1A1TSHRKDM4EHSD17B10HSD17B3 | |
| SCHEMBL31432763 | 0.89 | ALDH1A1 (0.51) | ALDH1A1TSHRKDM4EHSD17B10GAA | |
| SCHEMBL31432714 | 0.89 | ALDH1A1 (0.51) | ALDH1A1TSHRKDM4EHSD17B10GAA | |
| SCHEMBL31542160 | 0.89 | ALDH1A1 (0.51) | ALDH1A1TSHRKDM4EHSD17B10GAA | |
| SCHEMBL31432952 | 0.88 | HSD17B3 (0.51) | ALDH1A1TSHRKDM4EHSD17B10HSD17B3 | |
| SCHEMBL31432782 | 0.87 | HSD17B3 (0.50) | HSD17B3SLC6A3SLC6A4SLC6A2ROCK2 | |
| SCHEMBL31432828 | 0.87 | HSD17B3 (0.50) | HSD17B3SLC6A3SLC6A4SLC6A2ROCK2 | |
| SCHEMBL31432861 | 0.82 | HSD17B3 (0.48) | ALDH1A1TSHRHSD17B3SLC6A3SLC6A4 | |
| SCHEMBL31432839 | 0.80 | HSD17B3 (0.51) | ALDH1A1HSD17B3SLC6A3SLC6A4SLC6A2 | |
| SCHEMBL31432712 | 0.78 | NAMPT (0.43) | HSD17B3LMNAL3MBTL1ABHD6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4545138-A1 | HETEROCYCLIC COMPOUNDS AS BLT2 AGONISTS AND THEIR MEDICAL USE | Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. (DE) | 2025-04-30 | — | — | EP | disclosed |