Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B3 | P37058 | 2/20 | 0.51 |
| ▸ | SLC6A3 | Q01959 | 4/20 | 0.49 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.49 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.49 |
| ▸ | NAMPT | P43490 | 2/20 | 0.43 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.42 |
| ▸ | CSF1R | P07333 | 1/20 | 0.42 |
| ▸ | KDR | P35968 | 1/20 | 0.42 |
| ▸ | FLT3 | P36888 | 1/20 | 0.42 |
| ▸ | GSK3A | P49840 | 1/20 | 0.42 |
| ▸ | GSK3B | P49841 | 1/20 | 0.42 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.42 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.42 |
| ▸ | SLK | Q9H2G2 | 1/20 | 0.42 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.42 |
| ▸ | DPP8 | Q6V1X1 | 8/20 | 0.40 |
| ▸ | DPP9 | Q86TI2 | 8/20 | 0.40 |
| ▸ | DPP7 | Q9UHL4 | 8/20 | 0.40 |
| ▸ | DPP4 | P27487 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31432828 | 0.90 | HSD17B3 (0.50) | HSD17B3SLC6A3SLC6A4SLC6A2NAMPT | |
| SCHEMBL31432782 | 0.90 | HSD17B3 (0.50) | HSD17B3SLC6A3SLC6A4SLC6A2NAMPT | |
| SCHEMBL31432883 | 0.88 | ALDH1A1 (0.53) | HSD17B3SLC6A3SLC6A4SLC6A2ROCK2 | |
| SCHEMBL31432781 | 0.88 | ALDH1A1 (0.53) | HSD17B3SLC6A3SLC6A4SLC6A2ROCK2 | |
| SCHEMBL31432712 | 0.87 | NAMPT (0.43) | HSD17B3NAMPTDPP8DPP9DPP7 | |
| SCHEMBL31432839 | 0.82 | HSD17B3 (0.51) | HSD17B3SLC6A3SLC6A4SLC6A2NAMPT | |
| SCHEMBL31432861 | 0.79 | HSD17B3 (0.48) | HSD17B3SLC6A3SLC6A4SLC6A2ROCK2 | |
| SCHEMBL31432718 | 0.77 | DPP7 (0.44) | NAMPTDPP8DPP9DPP7DPP4 | |
| SCHEMBL31542161 | 0.77 | DPP7 (0.44) | NAMPTDPP8DPP9DPP7DPP4 | |
| SCHEMBL31432759 | 0.77 | DPP7 (0.44) | NAMPTDPP8DPP9DPP7DPP4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025088073-A1 | HETEROCYCLIC COMPOUNDS AS BLT2 AGONISTS AND THEIR MEDICAL USE | Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. (DE) | 2025-05-01 | — | — | WO | disclosed |
| EP-4545138-A1 | HETEROCYCLIC COMPOUNDS AS BLT2 AGONISTS AND THEIR MEDICAL USE | Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. (DE) | 2025-04-30 | — | — | EP | disclosed |