SCHEMBL31433140

SCHEMBL31433140

c1ccc(-c2cc3n(n2)C(C2CCCCC2)CCN3)cc1

nearest known ligand 0.39

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
CNR1 P21554 2/20 0.39
CNR2 P34972 2/20 0.39
BTK Q06187 3/20 0.36
NPC1 O15118 1/20 0.34
RAB9A P51151 1/20 0.34
ADORA1 P30542 2/20 0.34
ADORA3 P0DMS8 1/20 0.34
ADORA2A P29274 1/20 0.34
ADORA2B P29275 1/20 0.34
CDC7 O00311 1/20 0.34
DBF4 Q9UBU7 1/20 0.34
PDE4D Q08499 1/20 0.34
HPGD P15428 1/20 0.33
NSD3 Q9BZ95 1/20 0.33
MAPT P10636 1/20 0.32
PKM P14618 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24828101 0.78 NSD3 (0.39) CNR1CNR2NPC1RAB9APDE4D
SCHEMBL31433148 0.77 BTK (0.38) BTKNPC1RAB9ANSD3MAPT
SCHEMBL31433126 0.74 BTK (0.44) CNR1CNR2BTKNPC1RAB9A
SCHEMBL31433058 0.73 EGFR (0.46) BTK
SCHEMBL31433109 0.72 EGFR (0.40) BTKNPC1RAB9ANSD3MAPT
SCHEMBL31433152 0.72 MAOA (0.44) BTKNPC1RAB9AHPGDNSD3
SCHEMBL31433149 0.72 MAOB (0.43) BTKNPC1RAB9AMAPT
SCHEMBL31433081 0.71 GAA (0.38) RAB9AMAPTPKM
SCHEMBL31433117 0.71 MEN1 (0.44) NPC1RAB9AMAPTPKM
SCHEMBL31433153 0.69 NPC1 (0.39) BTKNPC1RAB9AHPGDNSD3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119638701-A Method for asymmetric hydrogenation of pyrazolopyrimidine polyazo aromatic compound by manganese catalysis 中国科学院大连化学物理研究所 2025-03-18 CN disclosed