SCHEMBL31433149

SCHEMBL31433149

Clc1ccc(C2CCNc3cc(-c4ccccc4)nn32)cc1

nearest known ligand 0.43

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
MAOB P27338 4/20 0.43
MAOA P21397 3/20 0.39
PRKCZ Q05513 2/20 0.39
ALOX15 P16050 1/20 0.39
TSHR P16473 1/20 0.39
SMN1; SMN2 Q16637 3/20 0.38
MEN1 O00255 2/20 0.38
KMT2A Q03164 2/20 0.38
LMNA P02545 2/20 0.38
MAPT P10636 1/20 0.38
STAT3 P40763 1/20 0.38
EGFR P00533 3/20 0.37
NPC1 O15118 2/20 0.36
RAB9A P51151 2/20 0.36
KDM4E B2RXH2 1/20 0.36
ERBB2 P04626 1/20 0.36
DDB1 Q16531 1/20 0.36
CRBN Q96SW2 1/20 0.36
BTK Q06187 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31433148 0.91 BTK (0.38) MAOBMAOAMEN1KMT2ALMNA
SCHEMBL31433109 0.88 EGFR (0.40) SMN1; SMN2MEN1KMT2ALMNAMAPT
SCHEMBL31433152 0.88 MAOA (0.44) MAOBMAOAALOX15SMN1; SMN2MEN1
SCHEMBL31433284 0.84 NPC1 (0.38) MEN1KMT2ALMNAMAPTNPC1
SCHEMBL31433080 0.84 MAPK1 (0.44) MAOBMAOASMN1; SMN2MEN1KMT2A
SCHEMBL31433058 0.84 EGFR (0.46) EGFRERBB2BTK
SCHEMBL31433157 0.82 MAPT (0.42) SMN1; SMN2MEN1KMT2ALMNAMAPT
SCHEMBL31433153 0.82 NPC1 (0.39) MAOBMAOAALOX15SMN1; SMN2MEN1
SCHEMBL31433073 0.81 MAOB (0.43) MAOBSMN1; SMN2MEN1KMT2ANPC1
SCHEMBL31433126 0.80 BTK (0.44) MEN1KMT2ALMNAMAPTNPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119638701-A Method for asymmetric hydrogenation of pyrazolopyrimidine polyazo aromatic compound by manganese catalysis 中国科学院大连化学物理研究所 2025-03-18 CN disclosed