Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.36 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.36 |
| ▸ | ALDH1A3 | P47895 | 1/20 | 0.35 |
| ▸ | NSD3 | Q9BZ95 | 1/20 | 0.35 |
| ▸ | BRD4 | O60885 | 1/20 | 0.34 |
| ▸ | BTK | Q06187 | 2/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | KHK | P50053 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31433148 | 0.88 | BTK (0.38) | NPC1RAB9AMEN1KMT2AMAPT | |
| SCHEMBL31433152 | 0.87 | MAOA (0.44) | NPC1RAB9AMEN1GAAKMT2A | |
| SCHEMBL31433149 | 0.84 | MAOB (0.43) | NPC1RAB9AMEN1KMT2AMAPT | |
| SCHEMBL31433109 | 0.84 | EGFR (0.40) | NPC1RAB9AMEN1GAAKMT2A | |
| SCHEMBL31433080 | 0.84 | MAPK1 (0.44) | MEN1GAAKMT2AMAPTKDM4E | |
| SCHEMBL31433153 | 0.82 | NPC1 (0.39) | NPC1RAB9AMEN1GAAKMT2A | |
| SCHEMBL31433058 | 0.81 | EGFR (0.46) | BTKSLC6A4SLC6A2SLC6A3 | |
| SCHEMBL31433073 | 0.80 | MAOB (0.43) | NPC1RAB9AMEN1KMT2AKDM4E | |
| SCHEMBL31433157 | 0.80 | MAPT (0.42) | NPC1RAB9AMEN1GAAKMT2A | |
| SCHEMBL31433113 | 0.79 | MAPK1 (0.44) | NPC1RAB9AMEN1GAAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119638701-A | Method for asymmetric hydrogenation of pyrazolopyrimidine polyazo aromatic compound by manganese catalysis | 中国科学院大连化学物理研究所 | 2025-03-18 | — | — | CN | disclosed |