Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IL23R | Q5VWK5 | 18/20 | 0.64 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.59 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31433169 | 0.98 | IL23R (0.66) | IL23R | |
| SCHEMBL30598170 | 0.92 | NPBWR1 (0.61) | IL23RPRMT1RXFP1 | |
| SCHEMBL29988116 | 0.91 | NPBWR1 (0.61) | IL23RRXFP1 | |
| SCHEMBL31433263 | 0.89 | NPBWR1 (0.65) | IL23R | |
| SCHEMBL31433256 | 0.88 | IL23R (0.62) | IL23R | |
| SCHEMBL29396822 | 0.87 | NPBWR1 (0.61) | IL23RRXFP1 | |
| SCHEMBL31433306 | 0.87 | NPBWR1 (0.69) | IL23R | |
| SCHEMBL31433230 | 0.87 | NPBWR1 (0.69) | IL23R | |
| SCHEMBL31226860 | 0.87 | NPBWR1 (0.64) | IL23RRXFP1 | |
| SCHEMBL31294865 | 0.87 | NPBWR1 (0.61) | IL23RRXFP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250074942-A1 | COMPOSITIONS AND METHODS FOR COVALENT PEPTIDE-BASED MODULATORS OF HLA-E | CALICO LIFE SCIENCES LLC (US) | 2025-03-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250074942-A1 | COMPOSITIONS AND METHODS FOR COVALENT PEPTIDE-BASED MODULATORS OF HLA-E | MICA, CD74, HLA-DRB1 | IL23R 710/4885PRMT1 1191/4885RXFP1 4125/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.