Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CXCR4 | P61073 | 9/20 | 0.59 |
| ▸ | C5AR1 | P21730 | 1/20 | 0.56 |
| ▸ | CTSL | P07711 | 2/20 | 0.54 |
| ▸ | CTSS | P25774 | 2/20 | 0.54 |
| ▸ | CTSK | P43235 | 2/20 | 0.54 |
| ▸ | IL23R | Q5VWK5 | 2/20 | 0.54 |
| ▸ | MC4R | P32245 | 1/20 | 0.53 |
| ▸ | MC5R | P33032 | 1/20 | 0.53 |
| ▸ | MC3R | P41968 | 1/20 | 0.53 |
| ▸ | MC1R | Q01726 | 1/20 | 0.53 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.53 |
| ▸ | GLP1R | P43220 | 3/20 | 0.52 |
| ▸ | GCGR | P47871 | 3/20 | 0.52 |
| ▸ | CTSH | P09668 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31433264 | 0.96 | CXCR4 (0.58) | CXCR4C5AR1CTSLCTSSCTSK | |
| SCHEMBL31433441 | 0.96 | CXCR4 (0.58) | CXCR4C5AR1CTSLCTSSCTSK | |
| SCHEMBL31433350 | 0.96 | CXCR4 (0.57) | CXCR4C5AR1CTSLCTSSCTSK | |
| SCHEMBL31433250 | 0.92 | CTSL (0.60) | CXCR4C5AR1CTSLCTSSCTSK | |
| SCHEMBL31433222 | 0.92 | CTSL (0.60) | CXCR4C5AR1CTSLCTSSCTSK | |
| SCHEMBL31433253 | 0.92 | CXCR4 (0.61) | CXCR4C5AR1CTSLCTSSCTSK | |
| SCHEMBL31433232 | 0.92 | CXCR4 (0.58) | CXCR4C5AR1IL23RMC4RMC5R | |
| SCHEMBL31433346 | 0.91 | CXCR4 (0.59) | CXCR4C5AR1CTSLCTSSCTSK | |
| SCHEMBL29838088 | 0.91 | CXCR4 (0.61) | CXCR4C5AR1CTSLCTSSCTSK | |
| SCHEMBL31433258 | 0.89 | CXCR4 (0.52) | CXCR4CTSLCTSSCTSKCTSH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250074942-A1 | COMPOSITIONS AND METHODS FOR COVALENT PEPTIDE-BASED MODULATORS OF HLA-E | CALICO LIFE SCIENCES LLC (US) | 2025-03-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250074942-A1 | COMPOSITIONS AND METHODS FOR COVALENT PEPTIDE-BASED MODULATORS OF HLA-E | MICA, CD74, HLA-DRB1 | CXCR4 429/4885C5AR1 1505/4885CTSL 588/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.