Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FNTA | P49354 | 7/20 | 0.47 |
| ▸ | FNTB | P49356 | 7/20 | 0.47 |
| ▸ | GRB2 | P62993 | 1/20 | 0.47 |
| ▸ | PGGT1B | P53609 | 2/20 | 0.42 |
| ▸ | DPP3 | Q9NY33 | 3/20 | 0.42 |
| ▸ | XIAP | P98170 | 1/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.39 |
| ▸ | ANPEP | P15144 | 1/20 | 0.38 |
| ▸ | LNPEP | Q9UIQ6 | 1/20 | 0.38 |
| ▸ | NAA50 | Q9GZZ1 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31433191 | 0.91 | GRB2 (0.46) | FNTAFNTBGRB2 | |
| SCHEMBL31433238 | 0.89 | GRB2 (0.51) | FNTAFNTBGRB2DPP3XIAP | |
| SCHEMBL31433252 | 0.88 | GRB2 (0.50) | FNTAFNTBGRB2PGGT1BDPP3 | |
| SCHEMBL31433277 | 0.88 | CAPN1 (0.42) | FNTAFNTBGRB2SLC6A2NAA50 | |
| SCHEMBL31433173 | 0.87 | ACE (0.44) | GRB2NAA50 | |
| SCHEMBL31433233 | 0.87 | MAPK8 (0.46) | GRB2 | |
| SCHEMBL31433348 | 0.87 | CALCR (0.45) | GRB2 | |
| SCHEMBL31433274 | 0.87 | APLNR (0.48) | GRB2 | |
| SCHEMBL31433187 | 0.86 | MAPK8 (0.43) | FNTAFNTBGRB2NAA50 | |
| SCHEMBL31433289 | 0.86 | MAPK8 (0.47) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250074942-A1 | COMPOSITIONS AND METHODS FOR COVALENT PEPTIDE-BASED MODULATORS OF HLA-E | CALICO LIFE SCIENCES LLC (US) | 2025-03-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250074942-A1 | COMPOSITIONS AND METHODS FOR COVALENT PEPTIDE-BASED MODULATORS OF HLA-E | MICA, CD74, HLA-DRB1 | FNTA 3629/4885FNTB 2486/4885GRB2 843/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.