Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRD1 | P41143 | 7/20 | 0.56 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.55 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.55 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.55 |
| ▸ | NTSR1 | P30989 | 3/20 | 0.53 |
| ▸ | REN | P00797 | 3/20 | 0.52 |
| ▸ | CALCR | P30988 | 2/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30812510 | 0.87 | OPRD1 (0.56) | OPRD1NTSR1REN | |
| SCHEMBL30812505 | 0.86 | OPRD1 (0.60) | OPRD1NTSR1REN | |
| SCHEMBL30812504 | 0.85 | OPRD1 (0.60) | OPRD1NTSR1REN | |
| SCHEMBL31433218 | 0.84 | OPRD1 (0.57) | OPRD1CALCR | |
| SCHEMBL30648479 | 0.84 | CALCR (0.59) | MAPK8MAPK9MAPK10CALCR | |
| SCHEMBL29688342 | 0.83 | CALCR (0.60) | OPRD1MAPK8MAPK9MAPK10CALCR | |
| SCHEMBL29707172 | 0.83 | CALCR (0.62) | OPRD1NTSR1CALCR | |
| SCHEMBL31461943 | 0.83 | OPRD1 (0.63) | OPRD1NTSR1 | |
| SCHEMBL30304242 | 0.83 | OPRD1 (0.60) | OPRD1NTSR1CALCR | |
| SCHEMBL31182798 | 0.82 | CALCR (0.64) | MAPK8MAPK9MAPK10CALCR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250074942-A1 | COMPOSITIONS AND METHODS FOR COVALENT PEPTIDE-BASED MODULATORS OF HLA-E | CALICO LIFE SCIENCES LLC (US) | 2025-03-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250074942-A1 | COMPOSITIONS AND METHODS FOR COVALENT PEPTIDE-BASED MODULATORS OF HLA-E | MICA, CD74, HLA-DRB1 | OPRD1 3640/4885MAPK8 4358/4885MAPK9 3139/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.