Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAMP3 | O60896 | 12/20 | 0.55 |
| ▸ | CALCR | P30988 | 12/20 | 0.55 |
| ▸ | APLNR | P35414 | 1/20 | 0.53 |
| ▸ | CXCR4 | P61073 | 2/20 | 0.50 |
| ▸ | NMUR2 | Q9GZQ4 | 3/20 | 0.50 |
| ▸ | NMUR1 | Q9HB89 | 3/20 | 0.50 |
| ▸ | C5AR1 | P21730 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31433260 | 0.99 | RAMP3 (0.55) | RAMP3CALCRAPLNRCXCR4NMUR2 | |
| SCHEMBL31433337 | 0.93 | RAMP3 (0.55) | RAMP3CALCRAPLNRCXCR4 | |
| SCHEMBL31254499 | 0.92 | RAMP3 (0.60) | RAMP3CALCRCXCR4NMUR2NMUR1 | |
| SCHEMBL31433178 | 0.91 | RAMP3 (0.52) | RAMP3CALCRAPLNRCXCR4NMUR2 | |
| SCHEMBL30884600 | 0.88 | RAMP3 (0.59) | RAMP3CALCRCXCR4 | |
| SCHEMBL31433200 | 0.87 | RAMP3 (0.51) | RAMP3CALCRAPLNRCXCR4NMUR2 | |
| SCHEMBL31433175 | 0.87 | APLNR (0.50) | RAMP3CALCRAPLNRNMUR2NMUR1 | |
| SCHEMBL31433176 | 0.87 | CAPN1 (0.52) | RAMP3CALCRAPLNRNMUR2NMUR1 | |
| SCHEMBL31433275 | 0.87 | CAPN1 (0.52) | RAMP3CALCRAPLNRNMUR2NMUR1 | |
| SCHEMBL31433226 | 0.87 | TFPI (0.48) | RAMP3CALCR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250074942-A1 | COMPOSITIONS AND METHODS FOR COVALENT PEPTIDE-BASED MODULATORS OF HLA-E | CALICO LIFE SCIENCES LLC (US) | 2025-03-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250074942-A1 | COMPOSITIONS AND METHODS FOR COVALENT PEPTIDE-BASED MODULATORS OF HLA-E | MICA, CD74, HLA-DRB1 | RAMP3 2637/4885CALCR 2817/4885APLNR 2565/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.