Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FOLH1 | Q04609 | 1/20 | 0.46 |
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.45 |
| ▸ | TERT | O14746 | 1/20 | 0.43 |
| ▸ | GSR | P00390 | 1/20 | 0.41 |
| ▸ | NOD1 | Q9Y239 | 3/20 | 0.40 |
| ▸ | NMT2 | O60551 | 1/20 | 0.40 |
| ▸ | NMT1 | P30419 | 1/20 | 0.40 |
| ▸ | SLC15A2 | Q16348 | 1/20 | 0.40 |
| ▸ | ERAP2 | Q6P179 | 4/20 | 0.39 |
| ▸ | LNPEP | Q9UIQ6 | 4/20 | 0.39 |
| ▸ | ERAP1 | Q9NZ08 | 2/20 | 0.39 |
| ▸ | CPB2 | Q96IY4 | 2/20 | 0.39 |
| ▸ | GNAI3 | P08754 | 1/20 | 0.38 |
| ▸ | GNAO1 | P09471 | 1/20 | 0.38 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.38 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.38 |
| ▸ | GSTK1 | Q9Y2Q3 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30828464 | 0.97 | FOLH1 (0.48) | FOLH1SLC6A5TERTGSRNOD1 | |
| SCHEMBL29895299 | 0.92 | NMT1 (0.49) | FOLH1SLC6A5TERTGSRNOD1 | |
| SCHEMBL29915442 | 0.92 | TERT (0.50) | FOLH1SLC6A5TERTGSRNOD1 | |
| SCHEMBL30445612 | 0.90 | NMT1 (0.49) | FOLH1SLC6A5TERTGSRNMT2 | |
| SCHEMBL30043210 | 0.90 | TERT (0.51) | FOLH1SLC6A5TERTGSRNOD1 | |
| SCHEMBL2887196 | 0.89 | TERT (0.52) | FOLH1SLC6A5TERTGSRNOD1 | |
| SCHEMBL2887200 | 0.89 | TERT (0.52) | FOLH1SLC6A5TERTGSRNOD1 | |
| SCHEMBL29678508 | 0.87 | NMT1 (0.49) | FOLH1SLC6A5TERTGSRNMT2 | |
| SCHEMBL31188441 | 0.86 | TERT (0.53) | FOLH1SLC6A5TERTGSRNOD1 | |
| SCHEMBL27164811 | 0.86 | FOLH1 (0.48) | FOLH1SLC6A5NMT2NMT1SLC15A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250074942-A1 | COMPOSITIONS AND METHODS FOR COVALENT PEPTIDE-BASED MODULATORS OF HLA-E | CALICO LIFE SCIENCES LLC (US) | 2025-03-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250074942-A1 | COMPOSITIONS AND METHODS FOR COVALENT PEPTIDE-BASED MODULATORS OF HLA-E | MICA, CD74, HLA-DRB1 | FOLH1 2388/4885SLC6A5 4187/4885TERT 4670/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.