Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | MIF | P14174 | 1/20 | 0.35 |
| ▸ | TYR | P14679 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | HSP90AA1 | P07900 | 6/20 | 0.35 |
| ▸ | HSP90AB1 | P08238 | 6/20 | 0.35 |
| ▸ | LTA4H | P09960 | 2/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 4/20 | 0.33 |
| ▸ | THRB | P10828 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3143354 | 0.81 | ATM (0.43) | ALDH1A1LMNAHTTNR1I2CYP2C9 | |
| SCHEMBL384122 | 0.74 | HSP90AA1 (0.63) | HSP90AA1HSP90AB1 | |
| SCHEMBL2564784 | 0.66 | ALDH1A1 (0.57) | ALDH1A1LMNAHTTNR1I2CYP2C9 | |
| SCHEMBL15396045 | 0.65 | ALDH1A1 (0.55) | ALDH1A1LMNAHTTNR1I2CYP2C9 | |
| SCHEMBL932909 | 0.64 | ALDH1A1 (0.50) | ALDH1A1LMNAHTTNR1I2CYP2C9 | |
| SCHEMBL28878410 | 0.64 | ALDH1A1 (0.50) | ALDH1A1LMNAHTTNR1I2CYP2C9 | |
| SCHEMBL27102396 | 0.64 | ALDH1A1 (0.50) | ALDH1A1LMNAHTTNR1I2CYP2C9 | |
| SCHEMBL11809725 | 0.64 | ALDH1A1 (0.53) | ALDH1A1LMNAHTTNR1I2CYP2C9 | |
| SCHEMBL5155008 | 0.64 | ALDH1A1 (0.48) | ALDH1A1LMNAHTTNR1I2CYP2C9 | |
| SCHEMBL7941367 | 0.62 | ALDH1A1 (0.47) | ALDH1A1LMNAHTTNR1I2CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100216782-A1 | HYDROXYBENZAMIDE DERIVATIVES AND THEIR USE AS INHIBITORS OF HSP90 | CHESSARI GIANNI | 2010-08-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100216782-A1 | HYDROXYBENZAMIDE DERIVATIVES AND THEIR USE AS INHIBITORS OF HSP90 | HSP90AB1, HSP90AB2P, HSP90AA1 | ALDH1A1 2150/4885LMNA 4208/4885HTT 153/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.