Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM5A | P29375 | 1/20 | 0.54 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | PKM | P14618 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | CSF1R | P07333 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31433576 | 0.87 | MAPT (0.47) | KDM5AKDM5BMAPTPKMKDM4E | |
| SCHEMBL15966771 | 0.80 | KDM5A (0.59) | KDM5AKDM5BKDM4EALDH1A1CSF1R | |
| SCHEMBL1060499 | 0.80 | KDM5A (0.59) | KDM5AKDM5BKDM4EALDH1A1CSF1R | |
| SCHEMBL11383772 | 0.79 | KDM4E (0.57) | KDM5AKDM5BKDM4ELMNAL3MBTL1 | |
| SCHEMBL25534187 | 0.78 | KDM5A (0.60) | KDM5AKDM5BMAPTPKMKDM4E | |
| SCHEMBL12492331 | 0.78 | KDM5A (0.54) | KDM5AKDM5BMAPTKDM4EALDH1A1 | |
| SCHEMBL10516655 | 0.77 | KDM5A (0.47) | KDM5AKDM5BMAPTPKMKDM4E | |
| SCHEMBL5526950 | 0.77 | KDM5A (0.62) | KDM5AKDM5BMAPTKDM4EALDH1A1 | |
| SCHEMBL4647482 | 0.76 | KDM5A (0.64) | KDM5AKDM5BKDM4E | |
| SCHEMBL5330015 | 0.76 | KDM5A (0.64) | KDM5AKDM5BKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025050016-A1 | TRICYCLIC QUINOLONE BCL6 BIFUNCTIONAL DEGRADERS | Treeline Biosciences, Inc. (US) | 2025-03-06 | — | — | WO | disclosed |