SCHEMBL31433733

SCHEMBL31433733

Fc1c(I)ccc(Br)c1C(F)(F)F

nearest known ligand 0.41

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
NOTUM Q6P988 1/20 0.41
SOS1 Q07889 1/20 0.39
ESR2 Q92731 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29915681 0.77 SOS1 (0.38) SOS1
SCHEMBL20824099 0.77 NOTUM (0.43) NOTUM
SCHEMBL17222991 0.77 SOS1 (0.38) SOS1
SCHEMBL2233270 0.74 SOS1 (0.33) SOS1
SCHEMBL5735193 0.74 SOS1 (0.36) SOS1
SCHEMBL8387241 0.74 NOTUM (0.41) NOTUMSOS1
SCHEMBL2487490 0.74 KDM1A (0.39)
SCHEMBL1507770 0.72
SCHEMBL22660409 0.71 NOTUM (0.38) NOTUMSOS1
SCHEMBL30504403 0.71 NOTUM (0.38) NOTUMSOS1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025050016-A1 TRICYCLIC QUINOLONE BCL6 BIFUNCTIONAL DEGRADERS Treeline Biosciences, Inc. (US) 2025-03-06 WO disclosed