Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 7/20 | 0.41 |
| ▸ | SOS1 | Q07889 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.31 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.31 |
| ▸ | MAOA | P21397 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.31 |
| ▸ | HTR3A | P46098 | 1/20 | 0.31 |
| ▸ | NT5E | P21589 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29915681 | 0.77 | SOS1 (0.38) | SOS1 | |
| SCHEMBL17222991 | 0.77 | SOS1 (0.38) | SOS1 | |
| SCHEMBL9693627 | 0.77 | NOTUM (0.43) | NOTUMCYP1A2CYP2C9CHRNB2CYP2B6 | |
| SCHEMBL27976350 | 0.74 | NOTUM (0.41) | NOTUM | |
| SCHEMBL5735193 | 0.74 | SOS1 (0.36) | SOS1 | |
| SCHEMBL31433733 | 0.74 | NOTUM (0.41) | NOTUMSOS1 | |
| SCHEMBL12804773 | 0.74 | NOTUM (0.41) | NOTUMCYP1A2CYP2C9CHRNB2CYP2B6 | |
| SCHEMBL2233270 | 0.74 | SOS1 (0.33) | SOS1 | |
| SCHEMBL2014602 | 0.74 | KDM1A (0.39) | — | |
| SCHEMBL31342136 | 0.74 | KDM1A (0.39) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5856274-A | 4-benzoyl isoxazoles and their use as herbicides | RHONE-POULENC AGRICULTURE LIMITED (GB) | 1999-01-05 | — | — | US | disclosed |
| EP-0682659-B1 | 4-Benzoyl isoxazole derivatives, their preparation and their use as herbicides | RHONE POULENC AGRICULTURE (GB) | 1997-04-16 | — | — | EP | disclosed |
| EP-0682659-A1 | 4-BENZOYL ISOXAZOLES AND THEIR USE AS HERBICIDES. | RHONE POULENC AGRICULTURE (GB) | 1995-11-22 | — | — | EP | disclosed |
| WO-1994018179-A1 | 4-BENZOYL ISOXAZOLES AND THEIR USE AS HERBICIDES | RHONE POULENC AGRICULTURE LTD (GB) | 1994-08-18 | — | — | WO | disclosed |