Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.64 |
| ▸ | POLB | P06746 | 1/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.49 |
| ▸ | AR | P10275 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.41 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31434014 | 0.88 | MAPT (0.62) | MAPTPOLBKMT2AALDH1A1KDM4E | |
| SCHEMBL20568495 | 0.82 | ALDH1A1 (0.55) | MAPTPOLBALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL2580162 | 0.82 | ALDH1A1 (0.53) | MAPTPOLBALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL9261071 | 0.82 | ALDH1A1 (0.54) | MAPTPOLBKMT2AALDH1A1KDM4E | |
| SCHEMBL21462498 | 0.80 | ALDH1A1 (0.63) | MAPTALDH1A1KDM4EARTP53 | |
| SCHEMBL29712314 | 0.80 | ALDH1A1 (0.63) | MAPTALDH1A1KDM4EARTP53 | |
| SCHEMBL31434094 | 0.78 | ALDH1A1 (0.49) | MAPTPOLBALDH1A1KDM4EAR | |
| SCHEMBL11639617 | 0.76 | ALDH1A1 (0.56) | MAPTALDH1A1KDM4ESMN1; SMN2LMNA | |
| SCHEMBL12291956 | 0.76 | ALDH1A1 (0.56) | POLBKMT2AALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL31433855 | 0.75 | MAPT (0.47) | MAPTPOLBKMT2AALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025050016-A1 | TRICYCLIC QUINOLONE BCL6 BIFUNCTIONAL DEGRADERS | Treeline Biosciences, Inc. (US) | 2025-03-06 | — | — | WO | disclosed |