Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.62 |
| ▸ | POLB | P06746 | 1/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.55 |
| ▸ | AR | P10275 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.40 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | ELANE | P08246 | 1/20 | 0.38 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.38 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31433767 | 0.88 | MAPT (0.64) | MAPTPOLBKMT2AARTP53 | |
| SCHEMBL21462437 | 0.84 | L3MBTL1 (0.45) | MAPTPOLBKMT2AL3MBTL1ALDH1A1 | |
| SCHEMBL20568530 | 0.82 | ALDH1A1 (0.43) | MAPTPOLBKMT2AL3MBTL1ALDH1A1 | |
| SCHEMBL20567987 | 0.81 | MAPT (0.61) | MAPTKMT2AARTP53L3MBTL1 | |
| SCHEMBL29712306 | 0.81 | MAPT (0.61) | MAPTKMT2AARTP53L3MBTL1 | |
| SCHEMBL23248374 | 0.77 | ALDH1A1 (0.42) | MAPTPOLBKMT2AL3MBTL1ALDH1A1 | |
| SCHEMBL11076507 | 0.75 | L3MBTL1 (0.53) | MAPTPOLBKMT2AL3MBTL1ALDH1A1 | |
| SCHEMBL9261071 | 0.74 | ALDH1A1 (0.54) | MAPTPOLBKMT2AALDH1A1KDM4E | |
| SCHEMBL31433855 | 0.74 | MAPT (0.47) | MAPTPOLBKMT2AARTP53 | |
| SCHEMBL11075024 | 0.72 | L3MBTL1 (0.49) | MAPTPOLBKMT2ATP53L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025050016-A1 | TRICYCLIC QUINOLONE BCL6 BIFUNCTIONAL DEGRADERS | Treeline Biosciences, Inc. (US) | 2025-03-06 | — | — | WO | disclosed |