Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DDB1 | Q16531 | 17/20 | 0.69 |
| ▸ | CRBN | Q96SW2 | 17/20 | 0.69 |
| ▸ | CTSD | P07339 | 1/20 | 0.36 |
| ▸ | CTSE | P14091 | 1/20 | 0.36 |
| ▸ | BACE1 | P56817 | 1/20 | 0.36 |
| ▸ | JAK1 | P23458 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31433800 | 0.92 | DDB1 (0.64) | DDB1CRBNBACE1 | |
| SCHEMBL31433939 | 0.91 | DDB1 (0.70) | DDB1CRBN | |
| SCHEMBL30830903 | 0.85 | DDB1 (0.69) | DDB1CRBN | |
| SCHEMBL23540247 | 0.84 | DDB1 (0.75) | DDB1CRBN | |
| SCHEMBL30776681 | 0.84 | DDB1 (0.75) | DDB1CRBN | |
| SCHEMBL30026749 | 0.84 | DDB1 (0.75) | DDB1CRBN | |
| SCHEMBL31236425 | 0.84 | CRBN (0.75) | DDB1CRBN | |
| SCHEMBL30768785 | 0.84 | DDB1 (0.75) | DDB1CRBN | |
| SCHEMBL30706226 | 0.84 | DDB1 (0.75) | DDB1CRBN | |
| SCHEMBL25586739 | 0.84 | DDB1 (0.75) | DDB1CRBN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025050016-A1 | TRICYCLIC QUINOLONE BCL6 BIFUNCTIONAL DEGRADERS | Treeline Biosciences, Inc. (US) | 2025-03-06 | — | — | WO | disclosed |