SCHEMBL31433789

SCHEMBL31433789

O=c1[nH]c2c(F)cc([N+](=O)[O-])cc2c(=O)o1

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
F7 P08709 1/20 0.40
F3 P13726 1/20 0.40
MEN1 O00255 4/20 0.37
KMT2A Q03164 4/20 0.37
ALDH1A1 P00352 2/20 0.37
MAPT P10636 2/20 0.37
L3MBTL1 Q9Y468 2/20 0.37
NPC1 O15118 1/20 0.37
LMNA P02545 1/20 0.37
HSP90AA1 P07900 1/20 0.37
RAB9A P51151 1/20 0.37
NPSR1 Q6W5P4 1/20 0.37
EPHX2 P34913 1/20 0.35
PARP1 P09874 2/20 0.35
CA12 O43570 2/20 0.35
CA9 Q16790 2/20 0.35
CYP1A2 P05177 1/20 0.34
CYP2C9 P11712 1/20 0.34
ELANE P08246 1/20 0.34
F2 P00734 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11760932 0.83 ALDH1A1 (0.54) MEN1KMT2AALDH1A1MAPTL3MBTL1
SCHEMBL4200416 0.82 SMN1; SMN2 (0.42) MEN1KMT2AALDH1A1MAPTL3MBTL1
SCHEMBL3039809 0.81 EPHX2 (0.41) F7F3MEN1KMT2AALDH1A1
SCHEMBL9061849 0.80 CYP19A1 (0.41) MEN1KMT2AALDH1A1MAPTL3MBTL1
SCHEMBL2061906 0.77 F2 (0.39) ALDH1A1LMNAPARP1F2CFD
SCHEMBL1515092 0.74 MAP2 (0.43) LMNANPSR1CYP1A2F2CFD
SCHEMBL3570986 0.74 F2 (0.37) F2CFD
SCHEMBL17767227 0.74 F2 (0.37) ALDH1A1MAPTLMNAPARP1CA9
SCHEMBL29530378 0.72 CA12 (0.58) MEN1KMT2AALDH1A1MAPTL3MBTL1
SCHEMBL870661 0.72 CA12 (0.58) MEN1KMT2AALDH1A1MAPTL3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025050016-A1 TRICYCLIC QUINOLONE BCL6 BIFUNCTIONAL DEGRADERS Treeline Biosciences, Inc. (US) 2025-03-06 WO disclosed