Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 4/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CA12 | O43570 | 2/20 | 0.35 |
| ▸ | CA9 | Q16790 | 2/20 | 0.35 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.35 |
| ▸ | PARP1 | P09874 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11760932 | 0.83 | ALDH1A1 (0.54) | LMNAMAPTALDH1A1TSHRTDP1 | |
| SCHEMBL31433789 | 0.82 | F7 (0.40) | LMNAMAPTALDH1A1MEN1KMT2A | |
| SCHEMBL12501369 | 0.81 | EPHX2 (0.41) | SMN1; SMN2LMNAMAPTALDH1A1TSHR | |
| SCHEMBL5280067 | 0.77 | ABCB1 (0.46) | SMN1; SMN2MAPTKMT2ACA12CA9 | |
| SCHEMBL17478972 | 0.76 | SMN1; SMN2 (0.55) | SMN1; SMN2LMNAMAPTALDH1A1TSHR | |
| SCHEMBL1202256 | 0.76 | GRIN2D (0.51) | SMN1; SMN2LMNAMAPTALDH1A1TSHR | |
| SCHEMBL30087001 | 0.74 | LMNA (0.38) | SMN1; SMN2LMNAMAPTTSHRMEN1 | |
| SCHEMBL3208633 | 0.74 | GSK3B (0.38) | LMNARAB9APARP1GRIN2DGRIN3B | |
| SCHEMBL2906293 | 0.74 | F2 (0.37) | GRIN2DGRIN3BGRIN1GRIN2AGRIN2B | |
| SCHEMBL14698434 | 0.74 | F2 (0.37) | ALDH1A1PARP1GRIN2DGRIN3BGRIN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 58 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116496248-A | Synthesis method of cyantraniliprole impurity | 江苏艾科姆检测有限公司 | 2023-07-28 | — | — | CN | claimed |
| US-11760728-B2 | Tead inhibitors and uses thereof | Ikena Oncology, Inc. (US) | 2023-09-19 | — | — | US | disclosed |
| CN-116496248-A | Synthesis method of cyantraniliprole impurity | 江苏艾科姆检测有限公司 | 2023-07-28 | — | — | CN | disclosed |
| US-9556141-B2 | Process for preparing N-substituted 1H-pyrazole-5-carboxylate compounds and derivatives thereof | BASF SE (DE) | 2017-01-31 | — | — | US | disclosed |
| US-9282741-B2 | Aniline type compounds | BASF SE (DE) | 2016-03-15 | — | — | US | disclosed |
| EP-2782910-B1 | PROCESS FOR PREPARING N-SUBSTITUTED 1H-PYRAZOLE-5-CARBOXYLATE COMPOUNDS AND DERIVATIVES THEREOF | BASF SE (DE) | 2016-02-03 | — | — | EP | disclosed |
| US-20150250174-A1 | USE OF N-THIO-ANTHRANILAMIDE COMPOUNDS ON CULTIVATED PLANTS | BASF SE (DE) | 2015-09-10 | — | — | US | disclosed |
| US-20150250173-A1 | PESTICIDALLY ACTIVE MIXTURES COMPRISING ANTHRANILAMIDE COMPOUNDS | BASF SE (DE) | 2015-09-10 | — | — | US | disclosed |
| US-20150250175-A1 | PESTICIDALLY ACTIVE MIXTURES COMPRISING ANTHRANILAMIDE COMPOUNDS | BASF SE (DE) | 2015-09-10 | — | — | US | disclosed |
| US-20150250172-A1 | USE OF ANTHRANILAMIDE COMPOUNDS IN SOIL AND SEED TREATMENT APPLICATION METHODS | BASF SE (DE) | 2015-09-10 | — | — | US | disclosed |
| US-20050282868-A1 | Substituted anthranilamides for controlling invertebrate pests | E. I. DU PONT DE NEMOURS AND COMPANY | 2005-12-22 | — | — | US | disclosed |
| EP-1549632-A4 | NOVEL THIOPHENE AMIDINES, COMPOSITIONS THEREOF, AND METHODS OF TREATING COMPLEMENT-MEDIATED DISEASES AND CONDITIONS | DIMENSIONAL PHARM INC (US) | 2005-11-09 | — | — | EP | disclosed |
| US-20050234081-A1 | Novel thiophene amidines, compositions thereof, and methods of treating complement-mediated diseases and conditions | SUBASINGHE NALIN | 2005-10-20 | — | — | US | disclosed |
| EP-1549632-A1 | NOVEL THIOPHENE AMIDINES, COMPOSITIONS THEREOF, AND METHODS OF TREATING COMPLEMENT-MEDIATED DISEASES AND CONDITIONS | 3-DIMENSIONAL PHARMACEUTICALS, INC. (US) | 2005-07-06 | — | — | EP | disclosed |
| WO-2005002627-A2 | CONJUGATED COMPLEMENT CASCADE INHIBITORS | ORTHO-MCNEIL PHARMACEUTICAL, INC. (US) | 2005-01-13 | — | — | WO | disclosed |
| US-20050004031-A1 | Conjugated complement cascade inhibitors | 3-DIMENSIONAL PHARMACEUTICALS, INC. | 2005-01-06 | — | — | US | disclosed |
| EP-1417176-A1 | SUBSTITUTED ANTHRANILAMIDES FOR CONTROLLING INVERTEBRATE PESTS | E. I. du Pont de Nemours and Company (US) | 2004-05-12 | — | — | EP | disclosed |
| US-20040009995-A1 | Novel thiophene amidines, compositions thereof, and methods of treating complement-mediated diseases and conditions | 3-DIMENSIONAL PHARMACEUTICALS, INC. | 2004-01-15 | — | — | US | disclosed |
| WO-2003099805-A1 | NOVEL THIOPHENE AMIDINES, COMPOSITIONS THEREOF, AND METHODS OF TREATING COMPLEMENT-MEDIATED DISEASES AND CONDITIONS | 3-DIMENSIONAL PHARMACEUTICALS, INC. (US) | 2003-12-04 | — | — | WO | disclosed |
| WO-2003016284-A1 | SUBSTITUTED ANTHRANILAMIDES FOR CONTROLLING INVERTEBRATE PESTS | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2003-02-27 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (9 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050234081-A1 | Novel thiophene amidines, compositions thereof, and methods of treating complement-mediated diseases and conditions | C5, C9, C1R | SMN1; SMN2 934/4885LMNA 4410/4885MAPT 3296/4885 |
| US-20040009995-A1 | Novel thiophene amidines, compositions thereof, and methods of treating complement-mediated diseases and conditions | C5, C9, C1R | SMN1; SMN2 1725/4885LMNA 4320/4885MAPT 2762/4885 |
| US-20150250174-A1 | USE OF N-THIO-ANTHRANILAMIDE COMPOUNDS ON CULTIVATED PLANTS | NAT1, TST, NIT2 | SMN1; SMN2 4588/4885LMNA 4139/4885MAPT 3117/4885 |
| US-20150250173-A1 | PESTICIDALLY ACTIVE MIXTURES COMPRISING ANTHRANILAMIDE COMPOUNDS | AADAC, ARSA, SIRT7 | SMN1; SMN2 2331/4885LMNA 4434/4885MAPT 3813/4885 |
| US-20050282868-A1 | Substituted anthranilamides for controlling invertebrate pests | ANTXR2, PRXL2A, F9 | SMN1; SMN2 2748/4885LMNA 3109/4885MAPT 4843/4885 |
| US-20050004031-A1 | Conjugated complement cascade inhibitors | C9, CFH, CFB | SMN1; SMN2 2736/4885LMNA 2162/4885MAPT 2992/4885 |
| US-20150250175-A1 | PESTICIDALLY ACTIVE MIXTURES COMPRISING ANTHRANILAMIDE COMPOUNDS | MCU, AGK, MLYCD | SMN1; SMN2 4665/4885LMNA 3904/4885MAPT 3497/4885 |
| US-20150250172-A1 | USE OF ANTHRANILAMIDE COMPOUNDS IN SOIL AND SEED TREATMENT APPLICATION METHODS | HRH3, DDT, ANTXR2 | SMN1; SMN2 3894/4885LMNA 3673/4885MAPT 3798/4885 |
| US-11760728-B2 | Tead inhibitors and uses thereof | TEAD2, TEAD3, TEAD4 | SMN1; SMN2 3736/4885LMNA 2907/4885MAPT 507/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.