Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIM1 | P11309 | 13/20 | 0.61 |
| ▸ | PIM2 | Q9P1W9 | 10/20 | 0.61 |
| ▸ | FLT3 | P36888 | 2/20 | 0.56 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.56 |
| ▸ | RET | P07949 | 2/20 | 0.49 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.49 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.49 |
| ▸ | KDR | P35968 | 1/20 | 0.49 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.45 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.42 |
| ▸ | AKT2 | P31751 | 1/20 | 0.42 |
| ▸ | BRAF | P15056 | 1/20 | 0.41 |
| ▸ | XPA | P23025 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31434367 | 0.94 | PIM1 (0.60) | PIM1PIM2FLT3PIM3RET | |
| SCHEMBL31434337 | 0.91 | PIM1 (0.74) | PIM1PIM2FLT3PIM3PDGFRB | |
| SCHEMBL31434365 | 0.81 | PIM1 (0.83) | PIM1PIM2FLT3PIM3RET | |
| SCHEMBL10091777 | 0.80 | PIM1 (0.64) | PIM1PIM2FLT3PIM3PDPK1 | |
| SCHEMBL31434376 | 0.80 | PIM1 (0.78) | PIM1PIM2FLT3PIM3RET | |
| SCHEMBL10091618 | 0.79 | PIM1 (0.76) | PIM1PIM2FLT3PIM3PDPK1 | |
| SCHEMBL10091854 | 0.78 | PIM1 (0.61) | PIM1PIM2FLT3PIM3RET | |
| SCHEMBL10091604 | 0.78 | PIM1 (0.63) | PIM1PIM2FLT3PIM3RET | |
| SCHEMBL10091603 | 0.78 | PIM1 (0.61) | PIM1PIM2FLT3PIM3PDPK1 | |
| SCHEMBL10091564 | 0.77 | PIM1 (0.60) | PIM1PIM2FLT3PIM3RET |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025085819-A1 | KINASE INHIBITOR COMPOSITIONS AND RELATED METHODS FOR THE TREATMENT OF A DISEASE | WASHINGTON UNIVERSITY (US) | 2025-04-24 | — | — | WO | disclosed |