Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIM1 | P11309 | 17/20 | 0.74 |
| ▸ | PIM2 | Q9P1W9 | 13/20 | 0.74 |
| ▸ | FLT3 | P36888 | 2/20 | 0.68 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.68 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.49 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.49 |
| ▸ | KDR | P35968 | 1/20 | 0.49 |
| ▸ | XPA | P23025 | 1/20 | 0.44 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.43 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31434286 | 0.91 | PIM1 (0.61) | PIM1PIM2FLT3PIM3PDGFRB | |
| SCHEMBL10091618 | 0.88 | PIM1 (0.76) | PIM1PIM2FLT3PIM3KEAP1 | |
| SCHEMBL31434367 | 0.87 | PIM1 (0.60) | PIM1PIM2FLT3PIM3PDGFRB | |
| SCHEMBL10091566 | 0.85 | PIM1 (0.70) | PIM1PIM2FLT3PIM3 | |
| SCHEMBL10091631 | 0.85 | PIM1 (0.70) | PIM1PIM2FLT3PIM3KEAP1 | |
| SCHEMBL10091634 | 0.85 | PIM1 (0.78) | PIM1PIM2FLT3PIM3 | |
| SCHEMBL10091543 | 0.85 | PIM1 (1.00) | PIM1PIM2FLT3PIM3PDGFRB | |
| SCHEMBL10091583 | 0.84 | PIM1 (0.94) | PIM1PIM2FLT3PIM3KEAP1 | |
| SCHEMBL10091581 | 0.83 | PIM1 (0.65) | PIM1PIM2FLT3PIM3KEAP1 | |
| SCHEMBL10091586 | 0.83 | PIM1 (0.76) | PIM1PIM2FLT3PIM3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025085819-A1 | KINASE INHIBITOR COMPOSITIONS AND RELATED METHODS FOR THE TREATMENT OF A DISEASE | WASHINGTON UNIVERSITY (US) | 2025-04-24 | — | — | WO | disclosed |