Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIM1 | P11309 | 11/20 | 0.60 |
| ▸ | PIM2 | Q9P1W9 | 8/20 | 0.55 |
| ▸ | FLT3 | P36888 | 2/20 | 0.51 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.51 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.45 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.44 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.44 |
| ▸ | KDR | P35968 | 1/20 | 0.44 |
| ▸ | RET | P07949 | 1/20 | 0.42 |
| ▸ | BRAF | P15056 | 2/20 | 0.41 |
| ▸ | XPA | P23025 | 2/20 | 0.41 |
| ▸ | CDK1 | P06493 | 1/20 | 0.40 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.40 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.40 |
| ▸ | CDK2 | P24941 | 1/20 | 0.40 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31434286 | 0.94 | PIM1 (0.61) | PIM1PIM2FLT3PIM3MAP4K4 | |
| SCHEMBL31434337 | 0.87 | PIM1 (0.74) | PIM1PIM2FLT3PIM3PDGFRB | |
| SCHEMBL31434314 | 0.81 | PIM1 (0.75) | PIM1PIM2FLT3PIM3RET | |
| SCHEMBL31434335 | 0.80 | PIM1 (0.78) | PIM1PIM2FLT3PIM3RET | |
| SCHEMBL10091560 | 0.79 | PIM1 (0.68) | PIM1PIM2FLT3PIM3PDGFRB | |
| SCHEMBL10091619 | 0.76 | PIM1 (0.68) | PIM1PIM2FLT3PIM3BRAF | |
| SCHEMBL10091602 | 0.76 | PIM1 (0.88) | PIM1PIM2FLT3PIM3PDGFRB | |
| SCHEMBL10091777 | 0.76 | PIM1 (0.64) | PIM1PIM2FLT3PIM3BRAF | |
| SCHEMBL699129 | 0.75 | PIM1 (1.00) | PIM1PIM2FLT3PIM3 | |
| SCHEMBL699128 | 0.75 | PIM1 (1.00) | PIM1PIM2FLT3PIM3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025085819-A1 | KINASE INHIBITOR COMPOSITIONS AND RELATED METHODS FOR THE TREATMENT OF A DISEASE | WASHINGTON UNIVERSITY (US) | 2025-04-24 | — | — | WO | disclosed |