Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.36 |
| ▸ | ACHE | P22303 | 3/20 | 0.35 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.34 |
| ▸ | CYP4F2 | P78329 | 2/20 | 0.33 |
| ▸ | CYP4A11 | Q02928 | 2/20 | 0.33 |
| ▸ | RXRA | P19793 | 1/20 | 0.33 |
| ▸ | RXRB | P28702 | 1/20 | 0.33 |
| ▸ | RXRG | P48443 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.32 |
| ▸ | FGFR1 | P11362 | 2/20 | 0.32 |
| ▸ | FLT3 | P36888 | 2/20 | 0.32 |
| ▸ | FGFR2 | P21802 | 1/20 | 0.32 |
| ▸ | FGFR4 | P22455 | 1/20 | 0.32 |
| ▸ | FGFR3 | P22607 | 1/20 | 0.32 |
| ▸ | KDR | P35968 | 1/20 | 0.32 |
| ▸ | DDR2 | Q16832 | 1/20 | 0.31 |
| ▸ | SYK | P43405 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5139638 | 0.79 | ACHE (0.43) | KDM5BACHEMCL1CYP4F2CYP4A11 | |
| Fluoride SCHEMBL14796503 | 0.79 | ACHE (0.43) | KDM5BACHEMCL1CYP4F2CYP4A11 | |
| SCHEMBL29218328 | 0.78 | ACHE (0.43) | KDM5BACHEMCL1CYP4F2CYP4A11 | |
| SCHEMBL6519027 | 0.78 | ACHE (0.46) | KDM5BACHEMCL1CYP4F2CYP4A11 | |
| SCHEMBL30320777 | 0.77 | ACHE (0.52) | KDM5BACHEMCL1CYP4F2CYP4A11 | |
| SCHEMBL1128591 | 0.75 | KDM5B (0.40) | KDM5BACHEMCL1CYP4F2CYP4A11 | |
| SCHEMBL17714250 | 0.75 | CYP4F2 (0.43) | KDM5BACHEMCL1CYP4F2CYP4A11 | |
| SCHEMBL28769997 | 0.75 | ACHE (0.40) | KDM5BACHEMCL1CYP4F2CYP4A11 | |
| SCHEMBL17018590 | 0.74 | KDM5B (0.36) | KDM5BACHEMCL1CYP4F2CYP4A11 | |
| SCHEMBL17021769 | 0.74 | KDM5B (0.36) | KDM5BACHEMCL1CYP4F2CYP4A11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025085347-A1 | IL4I1 INHIBITORS AND USES THEREOF | MERCK SHARP & DOHME LLC (US) | 2025-04-24 | — | — | WO | disclosed |