Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 3/20 | 0.40 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.39 |
| ▸ | CYP4F2 | P78329 | 2/20 | 0.37 |
| ▸ | CYP4A11 | Q02928 | 2/20 | 0.37 |
| ▸ | RXRA | P19793 | 1/20 | 0.37 |
| ▸ | RXRB | P28702 | 1/20 | 0.37 |
| ▸ | RXRG | P48443 | 1/20 | 0.37 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.37 |
| ▸ | FGFR1 | P11362 | 3/20 | 0.35 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.35 |
| ▸ | DDR2 | Q16832 | 1/20 | 0.35 |
| ▸ | FLT3 | P36888 | 2/20 | 0.35 |
| ▸ | FGFR2 | P21802 | 1/20 | 0.35 |
| ▸ | FGFR4 | P22455 | 1/20 | 0.35 |
| ▸ | FGFR3 | P22607 | 1/20 | 0.35 |
| ▸ | KDR | P35968 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | PSMB8 | P28062 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5139638 | 0.83 | ACHE (0.43) | ACHEKDM5BCYP4F2CYP4A11RXRA | |
| Fluoride SCHEMBL14796503 | 0.83 | ACHE (0.43) | ACHEKDM5BCYP4F2CYP4A11RXRA | |
| SCHEMBL29218328 | 0.82 | ACHE (0.43) | ACHEKDM5BCYP4F2CYP4A11RXRA | |
| SCHEMBL6519027 | 0.82 | ACHE (0.46) | ACHEKDM5BCYP4F2CYP4A11RXRA | |
| SCHEMBL30320777 | 0.79 | ACHE (0.52) | ACHEKDM5BCYP4F2CYP4A11RXRA | |
| SCHEMBL13035463 | 0.79 | OGA (0.45) | ACHEKDM5BCYP4F2CYP4A11RXRA | |
| SCHEMBL26162667 | 0.75 | ALDH1A1 (0.38) | ACHEKDM5BCYP4F2CYP4A11RXRA | |
| SCHEMBL24469879 | 0.75 | ACHE (0.40) | ACHEKDM5BCYP4F2CYP4A11RXRA | |
| SCHEMBL31434801 | 0.75 | KDM5B (0.36) | ACHEKDM5BCYP4F2CYP4A11RXRA | |
| SCHEMBL23535740 | 0.74 | MCL1 (0.47) | KDM5BCYP4F2CYP4A11RXRARXRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114685490-B | Pyrrolopyridine compound and application thereof | 南京再明医药有限公司 | 2025-03-28 | — | — | CN | disclosed |
| CN-114685490-A | Pyrrolopyridine compound and application thereof | 江苏先声药业有限公司 | 2022-07-01 | — | — | CN | disclosed |