Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2E1 | P05181 | 2/20 | 0.60 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.60 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.60 |
| ▸ | CYP2B6 | P20813 | 2/20 | 0.60 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.60 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 6/20 | 0.47 |
| ▸ | RAB9A | P51151 | 6/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.47 |
| ▸ | TP53 | P04637 | 2/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | CA12 | O43570 | 1/20 | 0.45 |
| ▸ | CA9 | Q16790 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.42 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31434590 | 0.85 | MAPT (0.47) | CYP2E1CYP2A6CYP2C9CYP2B6CYP2C19 | |
| SCHEMBL20810037 | 0.80 | TDP1 (0.59) | CYP2E1CYP2A6CYP2C9CYP2B6CYP2C19 | |
| SCHEMBL27163351 | 0.79 | CYP2E1 (0.60) | CYP2E1CYP2A6CYP2C9CYP2B6CYP2C19 | |
| SCHEMBL22191827 | 0.79 | CYP2C9 (0.60) | CYP2E1CYP2A6CYP2C9CYP2B6CYP2C19 | |
| SCHEMBL27163520 | 0.79 | CYP2A6 (0.72) | CYP2E1CYP2A6CYP2C9CYP2B6CYP2C19 | |
| SCHEMBL10162470 | 0.79 | CYP2A6 (0.72) | CYP2E1CYP2A6CYP2C9CYP2B6CYP2C19 | |
| SCHEMBL5901126 | 0.78 | RAB9A (0.54) | MAPTNPC1RAB9ASMN1; SMN2L3MBTL1 | |
| SCHEMBL22195036 | 0.78 | CYP2C9 (0.67) | CYP2E1CYP2A6CYP2C9CYP2B6CYP2C19 | |
| SCHEMBL20810154 | 0.77 | TDP1 (0.54) | CYP2E1CYP2A6CYP2C9CYP2B6CYP2C19 | |
| SCHEMBL22191578 | 0.77 | CYP2C9 (0.65) | CYP2E1CYP2A6CYP2C9CYP2B6CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025085347-A1 | IL4I1 INHIBITORS AND USES THEREOF | MERCK SHARP & DOHME LLC (US) | 2025-04-24 | — | — | WO | disclosed |