Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 3/20 | 0.45 |
| ▸ | RAB9A | P51151 | 6/20 | 0.44 |
| ▸ | NPC1 | O15118 | 5/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | NOTUM | Q6P988 | 2/20 | 0.42 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.42 |
| ▸ | PRKCA | P17252 | 1/20 | 0.42 |
| ▸ | GRK2 | P25098 | 1/20 | 0.42 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | CYP2E1 | P05181 | 1/20 | 0.40 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31434811 | 0.85 | CYP2E1 (0.60) | MAPTSMN1; SMN2CYP1A2POLBRAB9A | |
| SCHEMBL5901126 | 0.84 | RAB9A (0.54) | MAPTSMN1; SMN2CYP1A2POLBRAB9A | |
| SCHEMBL14707191 | 0.77 | RAB9A (0.61) | MAPTSMN1; SMN2CYP1A2POLBRAB9A | |
| SCHEMBL31434870 | 0.75 | NOTUM (0.71) | SMN1; SMN2CYP1A2POLBRAB9ANPC1 | |
| SCHEMBL189528 | 0.74 | SMN1; SMN2 (0.48) | MAPTSMN1; SMN2CYP1A2POLBRAB9A | |
| SCHEMBL9275897 | 0.73 | MEN1 (0.51) | SMN1; SMN2POLBRAB9ANPC1TDP1 | |
| SCHEMBL190189 | 0.72 | MAPT (0.48) | MAPTSMN1; SMN2CYP1A2POLBRAB9A | |
| SCHEMBL23930594 | 0.72 | RAB9A (0.50) | MAPTSMN1; SMN2CYP1A2POLBRAB9A | |
| SCHEMBL11852086 | 0.72 | NOTUM (0.53) | SMN1; SMN2POLBRAB9ANPC1L3MBTL1 | |
| SCHEMBL9131727 | 0.72 | ALDH1A1 (0.45) | MAPTRAB9ANPC1ALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025085347-A1 | IL4I1 INHIBITORS AND USES THEREOF | MERCK SHARP & DOHME LLC (US) | 2025-04-24 | — | — | WO | disclosed |