SCHEMBL31435159

SCHEMBL31435159

Cc1cn([C@H]2C[C@H](O)[C@@H](CO)O2)c(=O)n(CCCl)c1=O

nearest known ligand 0.77

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
TK1 P04183 3/20 0.46
LMNA P02545 2/20 0.46
SMN1; SMN2 Q16637 2/20 0.46
TK2 O00142 1/20 0.45
ALOX12 P18054 1/20 0.43
ADRA1A P35348 1/20 0.43
ADRB1 P08588 1/20 0.43
DNMT1 P26358 1/20 0.43
CYP1A2 P05177 1/20 0.42
CYP3A4 P08684 1/20 0.42
TSHR P16473 1/20 0.42
BLM P54132 1/20 0.42
PMP22 Q01453 1/20 0.42
NPSR1 Q6W5P4 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27759310 0.93 TK1 (0.44) TK1LMNASMN1; SMN2TK2ALOX12
SCHEMBL12718452 0.89 LMNA (0.48) TK1LMNASMN1; SMN2TK2ALOX12
SCHEMBL12718189 0.89 LMNA (0.48) TK1LMNASMN1; SMN2TK2ALOX12
SCHEMBL12718341 0.89 LMNA (0.48) TK1LMNASMN1; SMN2TK2ALOX12
SCHEMBL12749219 0.89 LMNA (0.48) TK1LMNASMN1; SMN2TK2ALOX12
SCHEMBL27592029 0.88 TK1 (0.49) TK1LMNASMN1; SMN2TK2ALOX12
SCHEMBL13949131 0.88 TK1 (0.49) TK1LMNASMN1; SMN2TK2ALOX12
SCHEMBL2056832 0.87 TK1 (0.50) TK1LMNASMN1; SMN2TK2ALOX12
SCHEMBL12749196 0.87 LMNA (0.47) TK1LMNASMN1; SMN2TK2ALOX12
SCHEMBL12718520 0.87 LMNA (0.47) TK1LMNASMN1; SMN2TK2ALOX12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025101722-A1 HIGH-AFFINITY ENGINEERED CHROMODOMAINS AXOIYA INC. (US) 2025-05-15 WO disclosed
WO-2025064811-A1 DNA-DEPENDENT DNA POLYMERASE COMPOSITIONS, METHODS, AND USES THEREOF REVISION BIO CORPORATION (US) 2025-03-27 WO disclosed
WO-2025064825-A1 DNA LIGASE COMPOSITIONS, METHODS, AND USES THEREOF REVISION BIO CORPORATION (US) 2025-03-27 WO disclosed