SCHEMBL31435229

SCHEMBL31435229

O=C(Nc1cccc(C(F)(F)F)c1)C1CCN(Cc2noc(-c3ccc(F)c(C4CC4)c3)n2)CC1

nearest known ligand 0.52

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
DCUN1D1 Q96GG9 6/20 0.52
UBE2M P61081 5/20 0.52
MEN1 O00255 4/20 0.47
KMT2A Q03164 4/20 0.47
ALDH1A1 P00352 1/20 0.47
KDM4E B2RXH2 2/20 0.46
LMNA P02545 2/20 0.45
HTT P42858 2/20 0.45
SMN1; SMN2 Q16637 2/20 0.45
USP2 O75604 1/20 0.45
TSHR P16473 1/20 0.45
HSD17B10 Q99714 1/20 0.45
L3MBTL1 Q9Y468 1/20 0.45
MAPT P10636 2/20 0.44
RECQL P46063 1/20 0.44
ACKR3 P25106 3/20 0.44
THRB P10828 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31435224 0.91 DCUN1D1 (0.53) DCUN1D1UBE2MMEN1KMT2AALDH1A1
SCHEMBL31435238 0.89 DCUN1D1 (0.56) DCUN1D1UBE2MMEN1KMT2AALDH1A1
SCHEMBL31435226 0.89 UBE2M (0.57) DCUN1D1UBE2MMEN1KMT2AALDH1A1
SCHEMBL31435220 0.86 UBE2M (0.60) DCUN1D1UBE2MMEN1KMT2AALDH1A1
SCHEMBL31435259 0.81 UBE2M (0.59) DCUN1D1UBE2MMEN1KMT2AALDH1A1
SCHEMBL31435222 0.79 UBE2M (0.46) DCUN1D1UBE2MMEN1KMT2AALDH1A1
SCHEMBL31435231 0.79 UBE2M (0.46) DCUN1D1UBE2MMEN1KMT2AALDH1A1
SCHEMBL31435225 0.79 UBE2M (0.46) DCUN1D1UBE2MMEN1KMT2AALDH1A1
SCHEMBL31435237 0.79 UBE2M (0.51) DCUN1D1UBE2MMEN1KMT2AALDH1A1
SCHEMBL31435221 0.77 UBE2M (0.50) DCUN1D1UBE2MMEN1KMT2AALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025090928-A9 COMPOUNDS FOR TREATMENT OF NEURODEGENERATIVE DISEASES AQUINNAH PHARMACEUTICALS, INC. (US) 2026-04-30 WO claimed
WO-2025090928-A1 COMPOUNDS FOR TREATMENT OF NEURODEGENERATIVE DISEASES AQUINNAH PHARMACEUTICALS, INC. (US) 2025-05-01 WO claimed
WO-2025090928-A9 COMPOUNDS FOR TREATMENT OF NEURODEGENERATIVE DISEASES AQUINNAH PHARMACEUTICALS, INC. (US) 2026-04-30 WO disclosed
WO-2025090928-A1 COMPOUNDS FOR TREATMENT OF NEURODEGENERATIVE DISEASES AQUINNAH PHARMACEUTICALS, INC. (US) 2025-05-01 WO disclosed