SCHEMBL3143526

SCHEMBL3143526

COc1ccc(C(=O)NC2CCCCC2)cc1OC

nearest known ligand 0.74

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 5/20 0.74
MEN1 O00255 4/20 0.74
ALPL P05186 1/20 0.74
ALDH1A1 P00352 1/20 0.67
TLR8 Q9NR97 1/20 0.61
TLR7 Q9NYK1 1/20 0.61
EPHX1 P07099 1/20 0.61
MAPT P10636 1/20 0.61
ALOX12 P18054 1/20 0.61
RAB9A P51151 2/20 0.60
NPC1 O15118 1/20 0.60
CYP1A2 P05177 1/20 0.60
HPGD P15428 1/20 0.60
CYP2C19 P33261 1/20 0.60
SMN1; SMN2 Q16637 1/20 0.60
CYP2D6 P10635 1/20 0.60
CYP2C9 P11712 1/20 0.60
L3MBTL1 Q9Y468 1/20 0.59

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11687058 1.00 KMT2A (0.74) KMT2AMEN1ALPLALDH1A1TLR8
Hydrochloric Acid SCHEMBL9639435 0.98 KMT2A (0.72) KMT2AMEN1ALPLALDH1A1TLR8
Hydrochloric Acid SCHEMBL9639562 0.97 KMT2A (0.70) KMT2AMEN1ALPLALDH1A1TLR8
SCHEMBL2473674 0.94 MEN1 (0.65) KMT2AMEN1ALPLALDH1A1CYP1A2
Hydrochloric Acid SCHEMBL9639296 0.92 MEN1 (0.64) KMT2AMEN1ALPLALDH1A1CYP1A2
SCHEMBL2225944 0.89 MAPT (0.62) KMT2AMEN1ALPLALDH1A1MAPT
SCHEMBL3134481 0.89 KMT2A (0.60) KMT2AMEN1ALPLALDH1A1MAPT
SCHEMBL23207634 0.88 RAB9A (0.61) KMT2AMEN1ALPLALDH1A1MAPT
SCHEMBL13425006 0.87 KMT2A (0.58) KMT2AMEN1ALPLALDH1A1MAPT
SCHEMBL23166045 0.87 MAPT (0.60) KMT2AMEN1ALPLALDH1A1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20100137445-A1 PLANT DISEASE CONTROL AGENT, AND PLANT DISEASE CONTROL METHOD SUMITOMO CHEMICAL COMPANY ,LIMITED 2010-06-03 US disclosed
US-20100137445-A1 PLANT DISEASE CONTROL AGENT, AND PLANT DISEASE CONTROL METHOD SUMITOMO CHEMICAL COMPANY ,LIMITED 2010-06-03 US disclosed
EP-2179651-A1 PLANT DISEASE CONTROL AGENT, AND PLANT DISEASE CONTROL METHOD Sumitomo Chemical Company, Limited (JP) 2010-04-28 EP disclosed
US-4342875-A STABILIZERS FOR OLEFIN POLYMERS CINCINNATI-MILACRON, INC. (US) 1982-08-03 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100137445-A1 PLANT DISEASE CONTROL AGENT, AND PLANT DISEASE CONTROL METHOD CBR3, CBR1, HDHD5 KMT2A 1467/4885MEN1 3173/4885ALPL 3704/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.