Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR1 | P21453 | 13/20 | 0.46 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.42 |
| ▸ | DYRK3 | O43781 | 1/20 | 0.41 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.41 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.41 |
| ▸ | PIM1 | P11309 | 1/20 | 0.41 |
| ▸ | MARK3 | P27448 | 1/20 | 0.41 |
| ▸ | PLK1 | P53350 | 1/20 | 0.41 |
| ▸ | CAMK2B | Q13554 | 1/20 | 0.41 |
| ▸ | CDC42BPA | Q5VT25 | 1/20 | 0.41 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.41 |
| ▸ | MINK1 | Q8N4C8 | 1/20 | 0.41 |
| ▸ | SRPK1 | Q96SB4 | 1/20 | 0.41 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.41 |
| ▸ | MAP3K20 | Q9NYL2 | 1/20 | 0.41 |
| ▸ | MAP4K5 | Q9Y4K4 | 1/20 | 0.41 |
| ▸ | MPL | P40238 | 5/20 | 0.41 |
| ▸ | S1PR3 | Q99500 | 2/20 | 0.39 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31435253 | 1.00 | S1PR1 (0.46) | S1PR1NOTUMDYRK3MAP4K4ERBB2 | |
| SCHEMBL31435243 | 0.91 | S1PR1 (0.41) | S1PR1DYRK3MAP4K4ERBB2PIM1 | |
| SCHEMBL34469816 | 0.86 | S1PR1 (0.43) | S1PR1DYRK3MAP4K4ERBB2PIM1 | |
| SCHEMBL31435230 | 0.84 | ACKR3 (0.46) | S1PR1 | |
| SCHEMBL31435231 | 0.84 | UBE2M (0.46) | — | |
| SCHEMBL31435258 | 0.84 | ACKR3 (0.46) | S1PR1 | |
| SCHEMBL31435222 | 0.84 | UBE2M (0.46) | — | |
| SCHEMBL31435225 | 0.84 | UBE2M (0.46) | — | |
| SCHEMBL31435252 | 0.84 | ACKR3 (0.38) | S1PR1MPL | |
| SCHEMBL31435233 | 0.84 | ACKR3 (0.38) | S1PR1MPL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025090928-A9 | COMPOUNDS FOR TREATMENT OF NEURODEGENERATIVE DISEASES | AQUINNAH PHARMACEUTICALS, INC. (US) | 2026-04-30 | — | — | WO | disclosed |
| WO-2025090928-A1 | COMPOUNDS FOR TREATMENT OF NEURODEGENERATIVE DISEASES | AQUINNAH PHARMACEUTICALS, INC. (US) | 2025-05-01 | — | — | WO | disclosed |