Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACKR3 | P25106 | 6/20 | 0.38 |
| ▸ | RXFP3 | Q9NSD7 | 1/20 | 0.36 |
| ▸ | UBE2M | P61081 | 1/20 | 0.35 |
| ▸ | DCUN1D1 | Q96GG9 | 1/20 | 0.35 |
| ▸ | S1PR1 | P21453 | 3/20 | 0.35 |
| ▸ | GSK3B | P49841 | 1/20 | 0.35 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.35 |
| ▸ | KDR | P35968 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | MPL | P40238 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31435252 | 1.00 | ACKR3 (0.38) | ACKR3RXFP3UBE2MDCUN1D1S1PR1 | |
| SCHEMBL31435225 | 0.91 | UBE2M (0.46) | ACKR3UBE2MDCUN1D1MEN1KMT2A | |
| SCHEMBL31435222 | 0.91 | UBE2M (0.46) | ACKR3UBE2MDCUN1D1MEN1KMT2A | |
| SCHEMBL31435231 | 0.91 | UBE2M (0.46) | ACKR3UBE2MDCUN1D1MEN1KMT2A | |
| SCHEMBL31435264 | 0.86 | ACKR3 (0.42) | ACKR3S1PR1GSK3BMAPK14KDR | |
| SCHEMBL31435223 | 0.86 | ACKR3 (0.42) | ACKR3S1PR1GSK3BMAPK14KDR | |
| SCHEMBL31435253 | 0.84 | S1PR1 (0.46) | S1PR1MPL | |
| SCHEMBL31435263 | 0.84 | S1PR1 (0.46) | S1PR1MPL | |
| SCHEMBL31435258 | 0.83 | ACKR3 (0.46) | ACKR3S1PR1GSK3BMAPK14 | |
| SCHEMBL31435243 | 0.83 | S1PR1 (0.41) | ACKR3S1PR1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025090928-A1 | COMPOUNDS FOR TREATMENT OF NEURODEGENERATIVE DISEASES | AQUINNAH PHARMACEUTICALS, INC. (US) | 2025-05-01 | — | — | WO | claimed |
| WO-2025090928-A1 | COMPOUNDS FOR TREATMENT OF NEURODEGENERATIVE DISEASES | AQUINNAH PHARMACEUTICALS, INC. (US) | 2025-05-01 | — | — | WO | disclosed |