Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACKR3 | P25106 | 3/20 | 0.42 |
| ▸ | GSK3B | P49841 | 2/20 | 0.40 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.40 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.37 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.37 |
| ▸ | S1PR1 | P21453 | 3/20 | 0.36 |
| ▸ | KDR | P35968 | 6/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | BRAF | P15056 | 4/20 | 0.36 |
| ▸ | MPL | P40238 | 1/20 | 0.34 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31435223 | 1.00 | ACKR3 (0.42) | ACKR3GSK3BMAPK14HDAC4HDAC6 | |
| SCHEMBL31435225 | 0.88 | UBE2M (0.46) | ACKR3KDM4EMEN1USP2LMNA | |
| SCHEMBL31435222 | 0.88 | UBE2M (0.46) | ACKR3KDM4EMEN1USP2LMNA | |
| SCHEMBL31435231 | 0.88 | UBE2M (0.46) | ACKR3KDM4EMEN1USP2LMNA | |
| SCHEMBL31435228 | 0.87 | GSK3B (0.43) | ACKR3GSK3BMAPK14S1PR1KDR | |
| SCHEMBL31435267 | 0.87 | GSK3B (0.43) | ACKR3GSK3BMAPK14S1PR1KDR | |
| SCHEMBL31435230 | 0.86 | ACKR3 (0.46) | ACKR3GSK3BMAPK14S1PR1 | |
| SCHEMBL31435258 | 0.86 | ACKR3 (0.46) | ACKR3GSK3BMAPK14S1PR1 | |
| SCHEMBL31435252 | 0.86 | ACKR3 (0.38) | ACKR3GSK3BMAPK14S1PR1KDR | |
| SCHEMBL31435233 | 0.86 | ACKR3 (0.38) | ACKR3GSK3BMAPK14S1PR1KDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025090928-A1 | COMPOUNDS FOR TREATMENT OF NEURODEGENERATIVE DISEASES | AQUINNAH PHARMACEUTICALS, INC. (US) | 2025-05-01 | — | — | WO | disclosed |