SCHEMBL31435328

SCHEMBL31435328

CC(C)(C)OC(=O)Nc1ccc(Br)c(C(F)(F)F)n1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.39
POLB P06746 1/20 0.39
GSK3B P49841 1/20 0.37
DYRK1A Q13627 1/20 0.37
NPC1 O15118 4/20 0.36
RAB9A P51151 4/20 0.36
MEN1 O00255 2/20 0.36
KMT2A Q03164 2/20 0.36
HTT P42858 1/20 0.36
PSMB8 P28062 1/20 0.36
RXFP1 Q9HBX9 1/20 0.36
LCK P06239 4/20 0.36
SCN9A Q15858 1/20 0.35
RECQL P46063 1/20 0.35
SMN1; SMN2 Q16637 1/20 0.35
CYP17A1 P05093 1/20 0.35
ATR Q13535 1/20 0.35
TRPA1 O75762 1/20 0.35
BCL2 P10415 1/20 0.35
GAA P10253 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24427690 1.00 LMNA (0.39) LMNAPOLBGSK3BDYRK1ANPC1
SCHEMBL21566100 0.83 GSK3B (0.40) GSK3BDYRK1ANPC1RAB9AMEN1
SCHEMBL30075068 0.83 GSK3B (0.40) GSK3BDYRK1ANPC1RAB9AMEN1
SCHEMBL1181120 0.81 RAB9A (0.52) LMNANPC1RAB9AKMT2ARXFP1
SCHEMBL24427691 0.81 RXFP1 (0.35) LMNAPOLBGSK3BDYRK1ARXFP1
SCHEMBL31627174 0.80 ATR (0.45) GSK3BDYRK1ANPC1RAB9AMEN1
SCHEMBL25961876 0.80 METAP1 (0.40) LMNAGSK3BDYRK1ANPC1RAB9A
SCHEMBL24102998 0.80 GSK3B (0.36) GSK3BDYRK1ANPC1RAB9AMEN1
SCHEMBL30420991 0.80 GSK3B (0.36) GSK3BDYRK1ANPC1RAB9AMEN1
SCHEMBL23107327 0.79 NPC1 (0.40) LMNAGSK3BDYRK1ANPC1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025090792-A1 AMIDE PRODRUGS AND USES THEREOF AUTOBAHN THERAPEUTICS, INC. (US) 2025-05-01 WO disclosed