Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNA7 | P36544 | 2/20 | 0.43 |
| ▸ | HTR3A | P46098 | 2/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.40 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.40 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.40 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.40 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.40 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.40 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.40 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.40 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.40 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.40 |
| ▸ | C1S | P09871 | 2/20 | 0.39 |
| ▸ | CFD | P00746 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29065460 | 0.84 | BCL2L1 (0.54) | HDAC1HDAC6HDAC3HDAC4HDAC7 | |
| SCHEMBL30416195 | 0.84 | BCL2L1 (0.54) | HDAC1HDAC6HDAC3HDAC4HDAC7 | |
| SCHEMBL155481 | 0.83 | HDAC1 (0.56) | CHRNA7HTR3AHDAC1HDAC6HDAC3 | |
| SCHEMBL3471180 | 0.79 | PTPN2 (0.52) | CHRNA7HTR3AHDAC1HDAC6HDAC3 | |
| SCHEMBL14562910 | 0.77 | HSD17B1 (0.49) | CHRNA7HTR3AHDAC1HDAC6HDAC3 | |
| SCHEMBL153935 | 0.76 | BCL2L1 (0.59) | CHRNA7HTR3AHDAC1HDAC6HDAC3 | |
| SCHEMBL31435451 | 0.76 | BCL2L1 (0.59) | CHRNA7HTR3AHDAC1HDAC6HDAC3 | |
| SCHEMBL3064054 | 0.74 | CHRNA7 (0.45) | CHRNA7HTR3AHDAC1HDAC6HDAC3 | |
| Phosphonic Acid SCHEMBL27130837 | 0.74 | PTPN2 (0.34) | HDAC1HDAC6HDAC3HDAC4HDAC7 | |
| SCHEMBL5889493 | 0.73 | HDAC4 (0.42) | HDAC1HDAC6HDAC3HDAC4KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119301127-A | 6-Oxo-decahydro pyrrolo [1,2-a ] [1,5] diazocine and 6-oxo-decahydro-4H-pyrrolo [2,1-d ] [1,5] thiaazacine derivatives as modulators of STAT3 and STAT6 for the treatment of cancer and inflammatory conditions | 瑞克鲁迪克斯制药股份有限公司 | 2025-01-10 | — | — | CN | disclosed |