Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.59 |
| ▸ | GPR35 | Q9HC97 | 3/20 | 0.55 |
| ▸ | BCKDK | O14874 | 1/20 | 0.46 |
| ▸ | CHRNA7 | P36544 | 2/20 | 0.46 |
| ▸ | HTR3A | P46098 | 2/20 | 0.46 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.46 |
| ▸ | PTPN2 | P17706 | 2/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 4/20 | 0.44 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.44 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.44 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.44 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.44 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.44 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.44 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.44 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.44 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.44 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.44 |
| ▸ | PLK4 | O00444 | 1/20 | 0.43 |
| ▸ | AURKA | O14965 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL153935 | 1.00 | BCL2L1 (0.59) | BCL2L1GPR35BCKDKCHRNA7HTR3A | |
| SCHEMBL14562910 | 0.87 | HSD17B1 (0.49) | BCL2L1GPR35BCKDKCHRNA7HTR3A | |
| SCHEMBL2897390 | 0.85 | BCL2L1 (0.59) | BCL2L1GPR35CHRNA7HTR3ATBXAS1 | |
| SCHEMBL29742282 | 0.85 | BCL2L1 (0.59) | BCL2L1GPR35CHRNA7HTR3ATBXAS1 | |
| SCHEMBL3064054 | 0.84 | CHRNA7 (0.45) | BCL2L1GPR35BCKDKCHRNA7HTR3A | |
| SCHEMBL155481 | 0.83 | HDAC1 (0.56) | CHRNA7HTR3APTPN2HDAC1HDAC3 | |
| SCHEMBL24139094 | 0.80 | GSK3B (0.45) | BCL2L1CHRNA7HTR3AHDAC1HDAC3 | |
| SCHEMBL15697571 | 0.79 | GPR35 (0.61) | BCL2L1GPR35TBXAS1HDAC1HDAC3 | |
| SCHEMBL8250577 | 0.79 | BCL2L1 (0.61) | BCL2L1GPR35TBXAS1PTPN2HDAC1 | |
| SCHEMBL1090344 | 0.78 | BCL2L1 (0.59) | BCL2L1GPR35CHRNA7HTR3ATBXAS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119301127-A | 6-Oxo-decahydro pyrrolo [1,2-a ] [1,5] diazocine and 6-oxo-decahydro-4H-pyrrolo [2,1-d ] [1,5] thiaazacine derivatives as modulators of STAT3 and STAT6 for the treatment of cancer and inflammatory conditions | 瑞克鲁迪克斯制药股份有限公司 | 2025-01-10 | — | — | CN | disclosed |