Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CG | P48736 | 2/20 | 0.40 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.40 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.40 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.40 |
| ▸ | PI4KA | P42356 | 1/20 | 0.40 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.40 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.34 |
| ▸ | C1S | P09871 | 1/20 | 0.34 |
| ▸ | FLT3 | P36888 | 3/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.31 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.31 |
| ▸ | FGFR3 | P22607 | 1/20 | 0.31 |
| ▸ | KDR | P35968 | 1/20 | 0.31 |
| ▸ | PIM1 | P11309 | 1/20 | 0.31 |
| ▸ | BRD4 | O60885 | 1/20 | 0.31 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.31 |
| ▸ | IKBKE | Q14164 | 1/20 | 0.31 |
| ▸ | TBK1 | Q9UHD2 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16320341 | 0.70 | PIK3CA (0.40) | PIK3CGPIK3CDPIK3CAPIK3CBPI4KA | |
| SCHEMBL3257666 | 0.67 | KDR (0.40) | PIK3CGPIK3CDPIK3CAPIK3CBPI4KA | |
| SCHEMBL3259305 | 0.67 | ALDH1A1 (0.49) | PIK3CGPIK3CDPIK3CAPIK3CBPI4KA | |
| SCHEMBL26765998 | 0.65 | FLT3 (0.38) | PIK3CGPIK3CDPIK3CAPIK3CBPI4KA | |
| SCHEMBL26766253 | 0.65 | IRAK1 (0.46) | PIK3CGPIK3CDPIK3CAPIK3CBPI4KA | |
| SCHEMBL16341282 | 0.65 | PIK3CD (0.36) | PIK3CGPIK3CDPIK3CAPIK3CBPI4KA | |
| SCHEMBL16320096 | 0.65 | PIK3CA (0.39) | PIK3CGPIK3CDPIK3CAPIK3CBPI4KA | |
| SCHEMBL16321724 | 0.64 | PIK3CD (0.35) | PIK3CGPIK3CDPIK3CAPIK3CBPI4KA | |
| SCHEMBL28575534 | 0.64 | MAPT (0.45) | PIK3CGPIK3CDPIK3CAPIK3CBPI4KA | |
| SCHEMBL25408417 | 0.64 | PIK3CD (0.43) | PIK3CGPIK3CDPIK3CAPIK3CBPI4KA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119661516-A | Bicyclic heterocyclic compounds, preparation method and medical application thereof | 华润医药研究院（深圳）有限公司 | 2025-03-21 | — | — | CN | disclosed |